Sandbox: Bone DDx: Difference between revisions
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* Located at the craniofacial bones, ribs, and proximal femur | * Located at the craniofacial bones, ribs, and proximal femur | ||
* Ground-glass matrix | |||
* Completely lucent or bubbly cystic expansile benign lesion | |||
* Well circumscribed with no periosteal reaction | |||
* Fibrocellular matrix of immature collagen | * Fibrocellular matrix of immature collagen | ||
Revision as of 14:57, 24 November 2015
- 10-20 yo patients
- Asymptomatic incidental finding on imaging studies
- Facial asymmetry, rib deformities, and leg-length discrepancy as late complication
- Located at the craniofacial bones, ribs, and proximal femur
- Ground-glass matrix
- Completely lucent or bubbly cystic expansile benign lesion
- Well circumscribed with no periosteal reaction
- Fibrocellular matrix of immature collagen
- Contains small irregularly shaped trabeculae of woven bone
- "Chinese characters" appearance
- Trabeculae not rimmed by osteoblasts
- Cartilaginous islands
- GNAS1 gene 10