Myelodysplastic syndrome pathophysiology: Difference between revisions
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*Dysgranulopoiesis | *Dysgranulopoiesis | ||
*Dysmegakaryocytopoiesis | *Dysmegakaryocytopoiesis | ||
===Dyserythropoiesis=== | |||
*Abnormal RBC formation | |||
====Nuclear features==== | |||
====Cytoplasmic features==== | |||
===Dysgranulopoiesis=== | ===Dysgranulopoiesis=== | ||
====Nuclear features==== | |||
====Cytoplasmic features==== | |||
===Dysmegakaryocytopoiesis=== | ===Dysmegakaryocytopoiesis=== | ||
====Nuclear features==== | |||
===Gallery=== | ===Gallery=== | ||
==Immunohistochemistry== | ==Immunohistochemistry== |
Revision as of 19:01, 8 December 2015
Myelodysplastic syndrome Microchapters |
Differentiating Myelodysplastic syndrome from other Diseases |
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Diagnosis |
Treatment |
Case Studies |
Myelodysplastic syndrome pathophysiology On the Web |
American Roentgen Ray Society Images of Myelodysplastic syndrome pathophysiology |
Risk calculators and risk factors for Myelodysplastic syndrome pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
On microscopic histopathological analysis, dyserythropoiesis, dysgranulopoiesis, and dysmegakaryocytopoiesis are findings of myelodysplastic syndrome.[1]
Pathophysiology
Pathogenesis
Genetics
Associated conditions
Myelodysplastic syndrome may be associated with:[2]
- Fanconi syndrome
- Diamond-blackfan syndrome
- Shwachman-diamond syndrome
Gross Pathology
On gross pathology, a well , subcapsular tumor may be suggestive of myelodysplastic syndrome.[3]
Microscopic Pathology
On microscopic histopathological analysis, characteristic findings of myelodysplastic syndrome include:[1]
- Dyserythropoiesis
- Dysgranulopoiesis
- Dysmegakaryocytopoiesis
Dyserythropoiesis
- Abnormal RBC formation
Nuclear features
Cytoplasmic features
Dysgranulopoiesis
Nuclear features
Cytoplasmic features
Dysmegakaryocytopoiesis
Nuclear features
Gallery
Immunohistochemistry
References
- ↑ 1.0 1.1 Histologic features of myelodysplastic syndromes. Librepathology (2015). http://librepathology.org/wiki/index.php/Myelodysplastic_syndromes. Accessed on December 8, 2015
- ↑ Associations of myelodysplastic syndromes. Librepathology (2015). http://librepathology.org/wiki/index.php/Myelodysplastic_syndromes. Accessed on December 8, 2015
- ↑ Associations of myelodysplastic syndromes. Librepathology (2015). http://librepathology.org/wiki/index.php/Myelodysplastic_syndromes. Accessed on December 8, 2015