Linitis plastica history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
Symptoms of linitis plastica may include dyspepsia, nausea, vomiting, early satiety, loss of appetite, weight loss, abdominal discomfort and sometimes diarrhea.<ref name=gh>Gastric linitis plastica. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=36273. Accessed on December 8, 2015.</ref><ref name=wi>Linitis plastica. Wikipedia. https://en.wikipedia.org/wiki/Linitis_plastica Accessed on December 8, 2015</ref> <ref name="pmid23984032">{{cite journal| author=Jafferbhoy S, Shiwani H, Rustum Q| title=Managing Gastric Linitis Plastica: Keep the scalpel sheathed. | journal=Sultan Qaboos Univ Med J | year= 2013 | volume= 13 | issue= 3 | pages= 451-3 | pmid=23984032 | doi= | pmc=PMC3749031 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23984032 }} </ref> A positive family history of diffuse gastric cancer may be present if it is the hereditary form of the disease. | Symptoms of linitis plastica may include [[dyspepsia]], nausea, vomiting, early satiety, loss of [[appetite]], weight loss, abdominal discomfort and sometimes [[diarrhea]].<ref name=gh>Gastric linitis plastica. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=36273. Accessed on December 8, 2015.</ref><ref name=wi>Linitis plastica. Wikipedia. https://en.wikipedia.org/wiki/Linitis_plastica Accessed on December 8, 2015</ref> <ref name="pmid23984032">{{cite journal| author=Jafferbhoy S, Shiwani H, Rustum Q| title=Managing Gastric Linitis Plastica: Keep the scalpel sheathed. | journal=Sultan Qaboos Univ Med J | year= 2013 | volume= 13 | issue= 3 | pages= 451-3 | pmid=23984032 | doi= | pmc=PMC3749031 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23984032 }} </ref> A positive family history of diffuse gastric cancer may be present if it is the hereditary form of the disease. | ||
==History and symptoms== | ==History and symptoms== | ||
*Diffuse gastric adenocarcinoma or linitis plastica remains asymptomatic for a long time before diagnosis. Therefore, when a patient presents with symptoms, the disease is usually in an advanced stage.<ref name="pmid23984032">{{cite journal| author=Jafferbhoy S, Shiwani H, Rustum Q| title=Managing Gastric Linitis Plastica: Keep the scalpel sheathed. | journal=Sultan Qaboos Univ Med J | year= 2013 | volume= 13 | issue= 3 | pages= 451-3 | pmid=23984032 | doi= | pmc=PMC3749031 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23984032 }} </ref> | *Diffuse gastric [[adenocarcinoma]] or linitis plastica remains asymptomatic for a long time before diagnosis. Therefore, when a patient presents with symptoms, the disease is usually in an advanced stage.<ref name="pmid23984032">{{cite journal| author=Jafferbhoy S, Shiwani H, Rustum Q| title=Managing Gastric Linitis Plastica: Keep the scalpel sheathed. | journal=Sultan Qaboos Univ Med J | year= 2013 | volume= 13 | issue= 3 | pages= 451-3 | pmid=23984032 | doi= | pmc=PMC3749031 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23984032 }} </ref> | ||
*Thickening and rigidity of the stomach wall makes the process of digestion difficult and the patient may complain of nausea, vomiting, bloating and sometimes diarrhea. | *Thickening and rigidity of the stomach wall makes the process of digestion difficult and the patient may complain of nausea, vomiting, [[bloating]] and sometimes diarrhea. | ||
*Patients may develop non specific symptoms like:<ref name=gh>Gastric linitis plastica. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=36273. Accessed on December 8, 2015.</ref><ref name=wi>Linitis plastica. Wikipedia. https://en.wikipedia.org/wiki/Linitis_plastica Accessed on December 8, 2015</ref><ref name="pmid23984032">{{cite journal| author=Jafferbhoy S, Shiwani H, Rustum Q| title=Managing Gastric Linitis Plastica: Keep the scalpel sheathed. | journal=Sultan Qaboos Univ Med J | year= 2013 | volume= 13 | issue= 3 | pages= 451-3 | pmid=23984032 | doi= | pmc=PMC3749031 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23984032 }} </ref> | *Patients may develop non specific symptoms like:<ref name=gh>Gastric linitis plastica. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=36273. Accessed on December 8, 2015.</ref><ref name=wi>Linitis plastica. Wikipedia. https://en.wikipedia.org/wiki/Linitis_plastica Accessed on December 8, 2015</ref><ref name="pmid23984032">{{cite journal| author=Jafferbhoy S, Shiwani H, Rustum Q| title=Managing Gastric Linitis Plastica: Keep the scalpel sheathed. | journal=Sultan Qaboos Univ Med J | year= 2013 | volume= 13 | issue= 3 | pages= 451-3 | pmid=23984032 | doi= | pmc=PMC3749031 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23984032 }} </ref> | ||
**[[Dyspepsia]] | **[[Dyspepsia]] | ||
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**Early satiety | **Early satiety | ||
**Weight loss | **Weight loss | ||
**Loss of appetite | **Loss of [[appetite]] | ||
**Abdominal discomfort | **Abdominal discomfort | ||
*A family history of linitis plastica may be present in patients with the hereditary diffuse adenocarcinoma, which is autosomal | *A family history of linitis plastica may be present in patients with the hereditary diffuse [[adenocarcinoma]], which is [[autosomal dominant]]ly inherited. | ||
==References== | ==References== | ||
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[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Revision as of 02:16, 14 December 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
Symptoms of linitis plastica may include dyspepsia, nausea, vomiting, early satiety, loss of appetite, weight loss, abdominal discomfort and sometimes diarrhea.[1][2] [3] A positive family history of diffuse gastric cancer may be present if it is the hereditary form of the disease.
History and symptoms
- Diffuse gastric adenocarcinoma or linitis plastica remains asymptomatic for a long time before diagnosis. Therefore, when a patient presents with symptoms, the disease is usually in an advanced stage.[3]
- Thickening and rigidity of the stomach wall makes the process of digestion difficult and the patient may complain of nausea, vomiting, bloating and sometimes diarrhea.
- Patients may develop non specific symptoms like:[1][2][3]
- A family history of linitis plastica may be present in patients with the hereditary diffuse adenocarcinoma, which is autosomal dominantly inherited.
References
- ↑ 1.0 1.1 Gastric linitis plastica. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=36273. Accessed on December 8, 2015.
- ↑ 2.0 2.1 Linitis plastica. Wikipedia. https://en.wikipedia.org/wiki/Linitis_plastica Accessed on December 8, 2015
- ↑ 3.0 3.1 3.2 Jafferbhoy S, Shiwani H, Rustum Q (2013). "Managing Gastric Linitis Plastica: Keep the scalpel sheathed". Sultan Qaboos Univ Med J. 13 (3): 451–3. PMC 3749031. PMID 23984032.