Pineal yolk sac tumor: Difference between revisions
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*Pure pineal yolk sac tumors secrete [[AFP]]. | *Pure pineal yolk sac tumors secrete [[AFP]]. | ||
*On microscopic histopathological analysis, pineal yolk sac tumor is characterized by poorly differentiated endothelium-like, cuboidal, or columnar cells. | *On microscopic histopathological analysis, pineal yolk sac tumor is characterized by poorly differentiated endothelium-like, cuboidal, or columnar cells. | ||
*Pineal yolk sac tumor is demonstrated by positivity to [[tumor markers]] such as [[AFP]] and [[Alpha 1-antitrypsin|AAT]]. | |||
*In upto 50% of cases, these tumors co-exist with other [[Germ cell tumor classification|germ cell tumors]].<ref name=pathiopy1>Pathology of pineal yolk sac tumour. Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pineal-yolk-sac-tumour. Accessed on December 9, 2015</ref> | *In upto 50% of cases, these tumors co-exist with other [[Germ cell tumor classification|germ cell tumors]].<ref name=pathiopy1>Pathology of pineal yolk sac tumour. Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pineal-yolk-sac-tumour. Accessed on December 9, 2015</ref> | ||
*Pineal yolk sac tumor may be associated with [[Down syndrome]].<ref name=associationspy1>Associations of pineal yolk sac tumor. Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pineal-yolk-sac-tumour. Accessed on December 8, 2015</ref> | *Pineal yolk sac tumor may be associated with [[Down syndrome]].<ref name=associationspy1>Associations of pineal yolk sac tumor. Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pineal-yolk-sac-tumour. Accessed on December 8, 2015</ref> | ||
*Common complications of pineal yolk sac tumor include [[obstructive hydrocephalus]] | |||
*Symptoms of pineal yolk sac tumor include [[headache]], [[nausea]], [[vomiting]], [[weakness]] | |||
==References== | ==References== | ||
Revision as of 14:29, 10 December 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Synonyms and keywords: Pineal yolk sac tumors; Pineal yolk sac tumour; Pineal yolk sac tumours; Pineal endodermal sinus tumor; Pineal endodermal sinus tumors; Pineal endodermal sinus tumour; Pineal endodermal sinus tumours; Pineal yolk sac carcinoma; Pineal yolk sac carcinomas; Pineal gland tumor; Germ cell tumor; Brain tumor
Overview
- Pineal yolk sac tumor is a rare type of extra gonadal yolk sac tumor. They make up a small fraction of all intracranial germ cell tumors and an even small fraction of pineal masses overall.[1]
- Pure pineal yolk sac tumors secrete AFP.
- On microscopic histopathological analysis, pineal yolk sac tumor is characterized by poorly differentiated endothelium-like, cuboidal, or columnar cells.
- Pineal yolk sac tumor is demonstrated by positivity to tumor markers such as AFP and AAT.
- In upto 50% of cases, these tumors co-exist with other germ cell tumors.[2]
- Pineal yolk sac tumor may be associated with Down syndrome.[3]
- Common complications of pineal yolk sac tumor include obstructive hydrocephalus
- Symptoms of pineal yolk sac tumor include headache, nausea, vomiting, weakness
References
- ↑ Pineal yolk sac tumour. Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pineal-yolk-sac-tumour. Accessed on December 8, 2015
- ↑ Pathology of pineal yolk sac tumour. Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pineal-yolk-sac-tumour. Accessed on December 9, 2015
- ↑ Associations of pineal yolk sac tumor. Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pineal-yolk-sac-tumour. Accessed on December 8, 2015