Myelodysplastic syndrome differential diagnosis: Difference between revisions
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Myelodysplastic syndrome must be differentiated from other diseases that cause [[anemia]], [[neutropenia]], and [[thrombocytopenia]], such as vitamin deficiencies, toxic exposure, biologic agents, heavy metals, chemotherapy, and infections.<ref name=Librepathology3>Differential diagnosis of myelodysplastic syndromes. Librepathology (2015). http://librepathology.org/wiki/index.php/Myelodysplastic_syndromes. Accessed on December 9, 2015</ref><ref name="MerrillSmith2011">{{cite journal|last1=Merrill|first1=Andrea L.|last2=Smith|first2=Hedy|title=Myelodysplastic Syndrome and Autoimmunity: A Case Report of an Unusual Presentation of Myelodysplastic Syndrome|journal=Case Reports in Hematology|volume=2011|year=2011|pages=1–4|issn=2090-6560|doi=10.1155/2011/560106}}</ref><ref name="DeZernSekeres2014">{{cite journal|last1=DeZern|first1=A. E.|last2=Sekeres|first2=M. A.|title=The Challenging World of Cytopenias: Distinguishing Myelodysplastic Syndromes From Other Disorders of Marrow Failure|journal=The Oncologist|volume=19|issue=7|year=2014|pages=735–745|issn=1083-7159|doi=10.1634/theoncologist.2014-0056}}</ref> | Myelodysplastic syndrome must be differentiated from other diseases that cause [[anemia]], [[neutropenia]], and [[thrombocytopenia]], such as vitamin deficiencies, toxic exposure, biologic agents, heavy metals, chemotherapy, and infections.<ref name=Librepathology3>Differential diagnosis of myelodysplastic syndromes. Librepathology (2015). http://librepathology.org/wiki/index.php/Myelodysplastic_syndromes. Accessed on December 9, 2015</ref><ref name="MerrillSmith2011">{{cite journal|last1=Merrill|first1=Andrea L.|last2=Smith|first2=Hedy|title=Myelodysplastic Syndrome and Autoimmunity: A Case Report of an Unusual Presentation of Myelodysplastic Syndrome|journal=Case Reports in Hematology|volume=2011|year=2011|pages=1–4|issn=2090-6560|doi=10.1155/2011/560106}}</ref><ref name="DeZernSekeres2014">{{cite journal|last1=DeZern|first1=A. E.|last2=Sekeres|first2=M. A.|title=The Challenging World of Cytopenias: Distinguishing Myelodysplastic Syndromes From Other Disorders of Marrow Failure|journal=The Oncologist|volume=19|issue=7|year=2014|pages=735–745|issn=1083-7159|doi=10.1634/theoncologist.2014-0056}}</ref> | ||
==Myelodysplastic syndrome differential diagnosis== | ==Myelodysplastic syndrome differential diagnosis== | ||
Myelodysplastic syndrome must be differentiated from other diseases that cause [[anemia]], [[neutropenia]], and [[thrombocytopenia]], such as:<ref name=Librepathology3>Differential diagnosis of myelodysplastic syndromes. Librepathology (2015). http://librepathology.org/wiki/index.php/Myelodysplastic_syndromes. Accessed on December 9, 2015</ref><ref name="MerrillSmith2011">{{cite journal|last1=Merrill|first1=Andrea L.|last2=Smith|first2=Hedy|title=Myelodysplastic Syndrome and Autoimmunity: A Case Report of an Unusual Presentation of Myelodysplastic Syndrome|journal=Case Reports in Hematology|volume=2011|year=2011|pages=1–4|issn=2090-6560|doi=10.1155/2011/560106}}</ref><ref name="DeZernSekeres2014">{{cite journal|last1=DeZern|first1=A. E.|last2=Sekeres|first2=M. A.|title=The Challenging World of Cytopenias: Distinguishing Myelodysplastic Syndromes From Other Disorders of Marrow Failure|journal=The Oncologist|volume=19|issue=7|year=2014|pages=735–745|issn=1083-7159|doi=10.1634/theoncologist.2014-0056}}</ref> | Myelodysplastic syndrome must be differentiated from other diseases that cause [[anemia]], [[neutropenia]], and [[thrombocytopenia]], such as: [[aplastic anemia]], [[fanconi anemia]], [[pure red cell aplasia]], [[Shwachman-Diamond syndrome]], [[paroxysmal nocturnal hemoglobinuria]], [[parvovirus B19|Parovirus B19 infection]] | ||
<ref name=Librepathology3>Differential diagnosis of myelodysplastic syndromes. Librepathology (2015). http://librepathology.org/wiki/index.php/Myelodysplastic_syndromes. Accessed on December 9, 2015</ref><ref name="MerrillSmith2011">{{cite journal|last1=Merrill|first1=Andrea L.|last2=Smith|first2=Hedy|title=Myelodysplastic Syndrome and Autoimmunity: A Case Report of an Unusual Presentation of Myelodysplastic Syndrome|journal=Case Reports in Hematology|volume=2011|year=2011|pages=1–4|issn=2090-6560|doi=10.1155/2011/560106}}</ref><ref name="DeZernSekeres2014">{{cite journal|last1=DeZern|first1=A. E.|last2=Sekeres|first2=M. A.|title=The Challenging World of Cytopenias: Distinguishing Myelodysplastic Syndromes From Other Disorders of Marrow Failure|journal=The Oncologist|volume=19|issue=7|year=2014|pages=735–745|issn=1083-7159|doi=10.1634/theoncologist.2014-0056}}</ref> | |||
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*[[Paroxysmal nocturnal hemoglobinuria]] | *[[Paroxysmal nocturnal hemoglobinuria]] | ||
*Parovirus B19 infection | *[[Parvovirus B19|Parovirus B19 infection]] | ||
*Myeloproliferative | *[[Myeloproliferative neoplasm]] | ||
*Toxic exposures | *Toxic exposures | ||
*Biologic agents | *Biologic agents | ||
*Heavy metals | *[[Heavy metals]] | ||
*Chemotherapy | *[[Chemotherapy]] | ||
| style="padding: 5px 5px; background: #F5F5F5; text-align:left;"| | | style="padding: 5px 5px; background: #F5F5F5; text-align:left;"| | ||
*Nutritional deficiency | *Nutritional deficiency | ||
:*Vitamin B12 defeciency | :*[[Vitamin B12|Vitamin B12 defeciency]] | ||
:*Folate defeciency | |||
:*[[Folic acid detailed information|Folate defeciency]] | |||
*Infections | *Infections | ||
|} | |} |
Revision as of 02:58, 14 December 2015
Myelodysplastic syndrome Microchapters |
Differentiating Myelodysplastic syndrome from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
Myelodysplastic syndrome must be differentiated from other diseases that cause anemia, neutropenia, and thrombocytopenia, such as vitamin deficiencies, toxic exposure, biologic agents, heavy metals, chemotherapy, and infections.[1][2][3]
Myelodysplastic syndrome differential diagnosis
Myelodysplastic syndrome must be differentiated from other diseases that cause anemia, neutropenia, and thrombocytopenia, such as: aplastic anemia, fanconi anemia, pure red cell aplasia, Shwachman-Diamond syndrome, paroxysmal nocturnal hemoglobinuria, Parovirus B19 infection [1][2][3]
Inherited cytopenia | Acquired cytopenia | Reactive cytopenia |
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References
- ↑ 1.0 1.1 Differential diagnosis of myelodysplastic syndromes. Librepathology (2015). http://librepathology.org/wiki/index.php/Myelodysplastic_syndromes. Accessed on December 9, 2015
- ↑ 2.0 2.1 Merrill, Andrea L.; Smith, Hedy (2011). "Myelodysplastic Syndrome and Autoimmunity: A Case Report of an Unusual Presentation of Myelodysplastic Syndrome". Case Reports in Hematology. 2011: 1–4. doi:10.1155/2011/560106. ISSN 2090-6560.
- ↑ 3.0 3.1 DeZern, A. E.; Sekeres, M. A. (2014). "The Challenging World of Cytopenias: Distinguishing Myelodysplastic Syndromes From Other Disorders of Marrow Failure". The Oncologist. 19 (7): 735–745. doi:10.1634/theoncologist.2014-0056. ISSN 1083-7159.