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==Overview==
==Overview==
Linitis plastica may be caused by [[lye]] ingestion or metastatic infiltration of the stomach, mostly breast and [[lung carcinoma]].<ref name="RobbinsBasic">Robbins Basic Pathology, 8th Edition</ref>
The most common cause of linitis plastica is scirrhous [[adenocarcinoma]]. Linitis plastica may be caused by germline mutations in the ''CDH1'' ([[E-cadherin]]) gene.<ref name="RobbinsBasic">Robbins Basic Pathology, 8th Edition</ref><ref name=st>Linitis plastica. Radiopedia. http://radiopaedia.org/articles/linitis-plastica Accessed on January 20, 2016</ref>


==Causes==
==Causes==
Linitis plastica may be caused by [[lye]] ingestion or metastatic infiltration of the stomach, mostly breast and [[lung carcinoma]].<ref name="RobbinsBasic">Robbins Basic Pathology, 8th Edition</ref>
*The most common cause of linitis plastica is scirrhous adenocarcinoma.
*Linitis plastica may be caused by germline mutations in the ''CDH1'' ([[E-cadherin]]) gene.<ref name="RobbinsBasic">Robbins Basic Pathology, 8th Edition</ref><ref name=st>Linitis plastica. Radiopedia. http://radiopaedia.org/articles/linitis-plastica Accessed on January 20, 2016</ref>


==References==
==References==

Revision as of 17:05, 20 January 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]

Overview

The most common cause of linitis plastica is scirrhous adenocarcinoma. Linitis plastica may be caused by germline mutations in the CDH1 (E-cadherin) gene.[1][2]

Causes

  • The most common cause of linitis plastica is scirrhous adenocarcinoma.
  • Linitis plastica may be caused by germline mutations in the CDH1 (E-cadherin) gene.[1][2]

References

  1. 1.0 1.1 Robbins Basic Pathology, 8th Edition
  2. 2.0 2.1 Linitis plastica. Radiopedia. http://radiopaedia.org/articles/linitis-plastica Accessed on January 20, 2016


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