Langerhans cell histiocytosis overview: Difference between revisions

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Revision as of 15:51, 21 December 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and symptoms

Physical Examination

Laboratory Findings

CT

MRI

Other Imaging Findings

Treatment

Medical therapy

Surgery

Prevention

References

Template:WikiDoc Sources

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 {{CMG}}; {{AE}} {{NM}}
 ==Overview==
-'''Langerhans Cell Histiocytosis (LCH)''' is a rare [[disease]] involving clonal proliferation of [[langerhans cell]]s, abnormal [[cell (biology)|cell]]s deriving from [[bone  marrow]] and capable of migrating from skin to [[lymph nodes]].  Clinically, its manifestations range from isolated bone lesions to [[systemic disease|multisystemic disease]].
-The disease is part of a group of clinical  syndromes called [[Histiocytosis|histiocytoses]], which are characterized by an abnormal proliferation of [[histiocyte]]s (an archaic term for dendritic cells and macrophages). These diseases are related to other forms of abnormal proliferation of white blood cells, such as [[leukemia]]s and [[lymphomas]].
-Langerhans Cell Histiocytosis  used to be called histiocytosis X, until it was renamed in 1985 by the Histiocyte society<ref>{{cite journal|author= |title=Histiocytosis syndromes in children. Writing Group of the Histiocyte Society |journal=Lancet |volume=1 |issue=8526 |pages=208-9|year=1987 |pmid=2880029}}</ref>
 ==Historical Perspective==

Langerhans cell histiocytosis overview: Difference between revisions

Revision as of 15:51, 21 December 2015

Contents

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and symptoms

Physical Examination

Laboratory Findings

CT

MRI

Other Imaging Findings

Treatment

Medical therapy

Surgery

Prevention

References

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