Pleomorphic xanthoastrocytoma: Difference between revisions
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==Overview== | ==Overview== | ||
Pleomorphic xanthoastrocytoma is a type of rare, [[astrocytoma|low-grade astrocytoma]] (''WHO Grade II'') found in young patients who typically present with [[temporal lobe epilepsy]].<ref name=overviewpxa1>Pleomorphic xanthoastrocytoma. Dr Bruno Di Muzio and A.Prof Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pleomorphic-xanthoastrocytoma. Accessed on December 29, 2015</ref> | Pleomorphic xanthoastrocytoma is a type of rare, [[astrocytoma|low-grade astrocytoma]] (''WHO Grade II'') found in young patients who typically present with [[temporal lobe epilepsy]].<ref name=overviewpxa1>Pleomorphic xanthoastrocytoma. Dr Bruno Di Muzio and A.Prof Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pleomorphic-xanthoastrocytoma. Accessed on December 29, 2015</ref> | ||
==Pathophysiology== | |||
===Gross Pathology=== | |||
On gross pathology, polymorphic xanthoastrocytoma is characterized by a well circumscribed mass, often with cystic component and involvement of the overlying [[leptomeninges]].<ref name=grosspxa1>Pathology of pleomorphic xanthoastrocytoma. Dr Bruno Di Muzio and A.Prof Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pleomorphic-xanthoastrocytoma. Accessed on December 29, 2015</ref> | |||
==Differentiating Pleomorphic Xanthoastrocytoma from other Diseases== | ==Differentiating Pleomorphic Xanthoastrocytoma from other Diseases== | ||
Revision as of 16:26, 29 December 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Synonyms and keywords: Pleomorphic xanthoastrocytomas; PXA
Overview
Pleomorphic xanthoastrocytoma is a type of rare, low-grade astrocytoma (WHO Grade II) found in young patients who typically present with temporal lobe epilepsy.[1]
Pathophysiology
Gross Pathology
On gross pathology, polymorphic xanthoastrocytoma is characterized by a well circumscribed mass, often with cystic component and involvement of the overlying leptomeninges.[2]
Differentiating Pleomorphic Xanthoastrocytoma from other Diseases
Pleomorphic xanthoastrocytoma must be differentiated from:[3][4]
- Desmoplastic infantile ganglioglioma
- Neuroblastoma
- Extraventricular neurocytoma
- Dysembryoplastic neuroepithelial tumor (DNET)
- Ganglioglioma
- Oligodendroglioma
References
- ↑ Pleomorphic xanthoastrocytoma. Dr Bruno Di Muzio and A.Prof Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pleomorphic-xanthoastrocytoma. Accessed on December 29, 2015
- ↑ Pathology of pleomorphic xanthoastrocytoma. Dr Bruno Di Muzio and A.Prof Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pleomorphic-xanthoastrocytoma. Accessed on December 29, 2015
- ↑ Yano, Hirohito; Saigoh, Chiemi; Nakayama, Noriyuki; Hirose, Yoshinobu; Abe, Masato; Ohe, Naoyuki; Ozeki, Michio; Shinoda, Jun; Iwama, Toru (2013). "Mixed neuronal-glial tumor in the temporal lobe of an infant: a case report". Diagnostic Pathology. 8 (1): 164. doi:10.1186/1746-1596-8-164. ISSN 1746-1596.
- ↑ Differential diagnosis of pleomorphic xanthoastrocytoma. Dr Bruno Di Muzio and A.Prof Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/pleomorphic-xanthoastrocytoma. Accessed on December 29, 2015