Sporotrichosis pathophysiology: Difference between revisions
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*The frequently nonspecific histopathology may mimic other granulomatous diseases.<ref name="pmid25614735">{{cite journal| author=Mahajan VK| title=Sporotrichosis: an overview and therapeutic options. | journal=Dermatol Res Pract | year= 2014 | volume= 2014 | issue= | pages= 272376 | pmid=25614735 | doi=10.1155/2014/272376 | pmc=PMC4295339 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25614735 }} </ref> | *The frequently nonspecific histopathology may mimic other granulomatous diseases.<ref name="pmid25614735">{{cite journal| author=Mahajan VK| title=Sporotrichosis: an overview and therapeutic options. | journal=Dermatol Res Pract | year= 2014 | volume= 2014 | issue= | pages= 272376 | pmid=25614735 | doi=10.1155/2014/272376 | pmc=PMC4295339 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25614735 }} </ref> | ||
:*Histologic features: | :*Histologic features: | ||
*marked acute to chronic inflammatory response | |||
==References== | ==References== |
Revision as of 18:55, 11 January 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Alison Leibowitz [2]
Overview
Pathophysiology
Transmission
- S. schenckii is usually transmitted to the human host via posttraumatic inoculation. However, sporotrichosis may also develop as a result of spore inhalation, although this mode of transmission is infrequent.
- Modes of transmission either lead to direct inoculation or enable the entry of the fungus.
- Actions, such as handling thorny plants, sphagnum moss, bales of hay, or any plant or plant product that can cause skin trauma, may enable S. schenckii entry.
Pathogenesis
- The pathophysiology of sporotrichosis depends on the histological subtype.
- The frequently nonspecific histopathology may mimic other granulomatous diseases.[1]
- Histologic features:
- marked acute to chronic inflammatory response
References
- ↑ Mahajan VK (2014). "Sporotrichosis: an overview and therapeutic options". Dermatol Res Pract. 2014: 272376. doi:10.1155/2014/272376. PMC 4295339. PMID 25614735.