Mycosis fungoides classification: Difference between revisions

	Cutaneous T cell lymphoma Microchapters
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Classification Mycosis fungoides Sezary syndrome
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Revision as of 16:02, 19 January 2016

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Based on the organ involvement, cutaneous T cell lymphoma may be classified into mycosis fungoides (MF) and sézary syndrome (SS).^[1]

Based on the organ involvement, cutaneous T cell lymphoma may be classified into:^[1]

**Cutaneous T cell lymphoma classification^[1]**
Name	Description
Mycosis fungoides (MF)	Most common form of cutaneous T cell lymphoma Starts in the skin in areas of the body not usually exposed to the sun May appear as a scaly, pink or red rash or patches on the skin Signs can progress to skin tumours in more advanced cases
Sézary syndrome (SS)	Often the more aggressive form of cutaneous T cell lymphoma An advanced form of mycosis fungoides Affects skin, blood, and lymph nodes Large areas of the skin are affected Skin is often red, itchy, painful and peeling Skin tumours can also appear Entire body can be affected, also known as "red man syndrome"

**Cutaneous T cell lymphoma classification^[2]**
Name	Description
Primary or cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma	Characterized by localized or disseminated eruptive papules, nodules with tumors showing central ulceration, and necrosis or by superficial hyperkeratotic patches and plaques Dissemination to other visceral sites (lung, testis, CNS, and oral mucosa) possible Lymph nodes seldom affected Aggressive clinical course with median survival of 32 months
Primary cutaneous CD4-positive small/medium T-cell lymphoma	Clinical presentation is usually a solitary plaque or nodule, commonly on the face, neck, or upper trunk Involvement of lower extremities is rare There should be an absence of patches

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+{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
+|+ '''Cutaneous T cell lymphoma classification<ref name= seer.cancer> Cutaneous T cell lymphoma. Surveillance, Epidemiology, and End Results . http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd52f7/ Accessed on January 19, 2016</ref>'''
+! style="background: #4479BA;; color:#FFF;" | Name
+! style="background: #4479BA;; color:#FFF;" | Description
+|-
+| style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | '''Primary or cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma'''
+| style="padding: 5px 5px; background: #F5F5F5;" |
+* Characterized by localized or disseminated eruptive papules, nodules with tumors showing central ulceration, and necrosis or by superficial hyperkeratotic patches and plaques
+* Dissemination to other visceral sites (lung, testis, CNS, and oral mucosa) possible
+* Lymph nodes seldom affected
+* Aggressive clinical course with median survival of 32 months
+|-
+| style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | ''' Primary cutaneous CD4-positive small/medium T-cell lymphoma'''
+| style="padding: 5px 5px; background: #F5F5F5;" |
+* Clinical presentation is usually a solitary plaque or nodule, commonly on the face, neck, or upper trunk
+* Involvement of lower extremities is rare
+* There should be an absence of patches
+|}
 ==References==
 {{reflist|2}}