Sandbox: Kaposi 2: Difference between revisions

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* The optimal therapy for Kaposi's sarcoma depends on multiple factors which include:  
* The optimal therapy for Kaposi's sarcoma depends on multiple factors which include:<ref name="pmid22677687">{{cite journal| author=Fatahzadeh M| title=Kaposi sarcoma: review and medical management update. | journal=Oral Surg Oral Med Oral Pathol Oral Radiol | year= 2012 | volume= 113 | issue= 1 | pages= 2-16 | pmid=22677687 | doi=10.1016/j.tripleo.2011.05.011 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22677687  }} </ref>
:* The anatomical location of the tumor
:* The anatomical location of the tumor
:* The specific variant of Kaposi's sarcoma
:* The specific variant of Kaposi's sarcoma
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* Management strategies varies depending on the specific variant of Kaposi's sarcoma such as:
* Management strategies varies depending on the specific variant of Kaposi's sarcoma such as:
:* Classic Kaposi's sarcoma managemenet may range from no treatment to either radiotherapy, local interventions, or surgical excision.  
:* Classic Kaposi's sarcoma managemenet may range from no treatment to either radiotherapy, local therapeutic  interventions, or surgical excision.  
 
:* Iatrogenic Kaposi's sarcoma management focuses on modifying immunosuppressive therapy in addition to local therapeutic interventions.  
 
:* Endemic Kaposi's sarcoma is primarily manage by systemic chemotherapy  
Therapy for KS aims to palliate symptoms, reduce tumor-associated edema, and improve esthetics and function.
:* There is no curative treatment for epidemic Kaposi's sarcoma; the mainstay management is HAART therapy which aims for the palliation and control of Kaposi's sarcoma progression.
Therapeutic approaches for classic KS range from no treatment to surgical excision, local interventions, and radiotherapy.
Management of iatrogenic KS often involves reduction or elimination of immunosuppressive therapy with or without local measures
Endemic KS is frequently responsive to systemic chemotherapy
Management of epidemic KS, in contrast, is not aimed at a cure but palliation and control of KS progression with HAART is considered an essential component of this process.

Revision as of 18:35, 21 January 2016

  • The optimal therapy for Kaposi's sarcoma depends on multiple factors which include:[1]
  • The anatomical location of the tumor
  • The specific variant of Kaposi's sarcoma
  • The rate of distribution and progression of Kaposi's sarcoma lesions
  • The patients clinical presentation
  • The efficacy and potential side effects of therapy
  • The presence or absence of HIV infection
  • The degree of immune suppression,
  • The presence of other comorbidities
  • The degree of host immune competence
  • The preference and prognosis of the patients
  • Management strategies varies depending on the specific variant of Kaposi's sarcoma such as:
  • Classic Kaposi's sarcoma managemenet may range from no treatment to either radiotherapy, local therapeutic interventions, or surgical excision.
  • Iatrogenic Kaposi's sarcoma management focuses on modifying immunosuppressive therapy in addition to local therapeutic interventions.
  • Endemic Kaposi's sarcoma is primarily manage by systemic chemotherapy
  • There is no curative treatment for epidemic Kaposi's sarcoma; the mainstay management is HAART therapy which aims for the palliation and control of Kaposi's sarcoma progression.
  1. Fatahzadeh M (2012). "Kaposi sarcoma: review and medical management update". Oral Surg Oral Med Oral Pathol Oral Radiol. 113 (1): 2–16. doi:10.1016/j.tripleo.2011.05.011. PMID 22677687.