Sandbox: ATL: Difference between revisions
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Host susceptibility | |||
Vertical infection with HTLV-1 as infant | |||
Attained at an age of >50 years | |||
Male sex | |||
HLA-A*26, HLA-B*4002, HLA-B*4006, and HLA-B*4801 (Japanese ATL) | |||
Co-infected with Strongyloides stercoralis | |||
Laboratory markers | |||
A high level of sil-2R, more than 500 U/ml | |||
A high level of anti-HTLV-1, titer more than × 1,024 | |||
A high level of circulating abnormal lymphocytes, more than 0.6% | |||
A low level of of anti-Tax reactivity | |||
A high level of white blood cell count, more than 9,000/μL | |||
Viral markers | |||
A higher HTLV-1 proviral load level, more than 4 copies per 100 PBMCs |
Revision as of 17:16, 24 January 2016
Host susceptibility
Vertical infection with HTLV-1 as infant
Attained at an age of >50 years
Male sex
HLA-A*26, HLA-B*4002, HLA-B*4006, and HLA-B*4801 (Japanese ATL)
Co-infected with Strongyloides stercoralis
Laboratory markers
A high level of sil-2R, more than 500 U/ml
A high level of anti-HTLV-1, titer more than × 1,024
A high level of circulating abnormal lymphocytes, more than 0.6%
A low level of of anti-Tax reactivity
A high level of white blood cell count, more than 9,000/μL
Viral markers
A higher HTLV-1 proviral load level, more than 4 copies per 100 PBMCs