Neoplastic meningitis medical therapy: Difference between revisions
Jump to navigation
Jump to search
| Line 20: | Line 20: | ||
*Chemotherapy can help in treatment of the total involved [[neuraxis]]. It may be administered systemically or intrathecally. | *Chemotherapy can help in treatment of the total involved [[neuraxis]]. It may be administered systemically or intrathecally. | ||
*Chemotherapeutic drugs can be given intrathecally either by lumbar puncture or via an intraventricular reservoir system. | *Chemotherapeutic drugs can be given intrathecally either by lumbar puncture or via an intraventricular reservoir system. | ||
*Accessing via the intraventricular reservoir system is preferred to lumbar puncture for the following reasons: | *Accessing via the intraventricular reservoir system is preferred to lumbar puncture for the following reasons:<ref name="Chamberlain2008">{{cite journal|last1=Chamberlain|first1=M. C.|title=Neoplastic Meningitis|journal=The Oncologist|volume=13|issue=9|year=2008|pages=967–977|issn=1083-7159|doi=10.1634/theoncologist.2008-0138}}</ref> | ||
:*Simple procedure | :*Simple procedure | ||
:*More comfortable for the patient | :*More comfortable for the patient | ||
:*Safer than repeated lumbar punctures | :*Safer than repeated lumbar punctures | ||
:*Better uniform distribution of the drug in the subarachnoid space | :*Better uniform distribution of the drug in the subarachnoid space | ||
*Chemotherapeutic agents that are routinely used include:<ref name="Chamberlain2008">{{cite journal|last1=Chamberlain|first1=M. C.|title=Neoplastic Meningitis|journal=The Oncologist|volume=13|issue=9|year=2008|pages=967–977|issn=1083-7159|doi=10.1634/theoncologist.2008-0138}}</ref> | |||
:*[[Methotrexate]] | |||
:*[[Cytarabine]] | |||
:*[[Thiotepa]] | |||
==References== | ==References== | ||
Revision as of 21:44, 22 January 2016
|
Neoplastic meningitis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Neoplastic meningitis medical therapy On the Web |
|
American Roentgen Ray Society Images of Neoplastic meningitis medical therapy |
|
Risk calculators and risk factors for Neoplastic meningitis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
The mainstay of therapy for neoplastic meningitis is intrathecal chemotherapy.[1]
Medical Therapy
The various treatment options for neoplastic meningitis include:[1]
Treatment of neoplastic meningitis | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Intrathecal chemotherapy | Radiotherapy | Surgery | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Chemotherapy
- The mainstay of therapy for neoplastic meningitis is intrathecal chemotherapy.[1]
- Chemotherapy can help in treatment of the total involved neuraxis. It may be administered systemically or intrathecally.
- Chemotherapeutic drugs can be given intrathecally either by lumbar puncture or via an intraventricular reservoir system.
- Accessing via the intraventricular reservoir system is preferred to lumbar puncture for the following reasons:[1]
- Simple procedure
- More comfortable for the patient
- Safer than repeated lumbar punctures
- Better uniform distribution of the drug in the subarachnoid space
- Chemotherapeutic agents that are routinely used include:[1]