Sandbox: ATL: Difference between revisions
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* Common risk factors in the development of adult T-cell leukemia among HTLV carriers include: | * Common risk factors in the development of adult T-cell leukemia among HTLV carriers include: | ||
* Vertical transmission of HTLV infection during infancy | :* Vertical transmission of HTLV infection during infancy | ||
* Male sex | :* Male sex | ||
* Specific human leukocyte antigens such as: | :* Specific human leukocyte antigens such as: | ||
:* HLA-A 26 | ::* HLA-A 26 | ||
:* HLA-B 4002 | ::* HLA-B 4002 | ||
:* HLA-B 4801 | ::* HLA-B 4801 | ||
:* Patients with a Strongyloides stercoralis co-infection | :* Patients with a Strongyloides stercoralis co-infection | ||
:* An elevated soluble interleukin-2 receptor levels (> 500 U/ml) | :* An elevated soluble interleukin-2 receptor levels (> 500 U/ml) | ||
Revision as of 17:29, 24 January 2016
- Common risk factors in the development of adult T-cell leukemia among HTLV carriers include:
- Vertical transmission of HTLV infection during infancy
- Male sex
- Specific human leukocyte antigens such as:
- HLA-A 26
- HLA-B 4002
- HLA-B 4801
- Patients with a Strongyloides stercoralis co-infection
- An elevated soluble interleukin-2 receptor levels (> 500 U/ml)
- An elevated anti-HTLV-1 titer
- An elevated HTLV proviral load level (> 4 copies per 100 peripheral blood mononuclear cells)
- An elevated WBC count (> 9,000/μL)
- An elevated abnormal lymphocyte count
- A decreased level of anti-Tax reactivity