Sandbox: ATL: Difference between revisions
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* Common risk factors in the development of adult T-cell leukemia among HTLV carriers include: | * Common risk factors in the development of adult T-cell leukemia among [[HTLV]] carriers include: | ||
:* Vertical transmission of HTLV infection during infancy | :* Vertical transmission of HTLV [[infection]] during [[infancy]] | ||
:* Male sex | :* Male sex | ||
:* Specific human leukocyte | :* Specific [[human leukocyte antigen]]s such as: | ||
::* HLA-A 26 | ::* [[HLA-A]] 26 | ||
::* HLA-B 4002 | ::* [[HLA-B]] 4002 | ||
::* HLA-B 4801 | ::* HLA-B 4801 | ||
:* Patients with a Strongyloides stercoralis co-infection | :* Patients with a [[Strongyloides stercoralis]] co-infection | ||
:* An elevated soluble interleukin-2 receptor levels (> 500 U/ml) | :* An elevated soluble [[interleukin-2 receptor]] levels (> 500 U/ml) | ||
:* An elevated anti-HTLV-1 titer | :* An elevated anti-HTLV-1 [[antibody]] [[titer]] | ||
:* An elevated HTLV proviral load level (> 4 copies per 100 peripheral blood mononuclear | :* An elevated HTLV proviral load level (> 4 copies per 100 peripheral blood [[mononuclear cell]]s) | ||
:* An elevated WBC count (> 9,000/μL) | :* An elevated [[WBC count]] (> 9,000/μL) | ||
:* An elevated abnormal lymphocyte count | :* An elevated abnormal [[lymphocyte]] count | ||
:* A decreased level of anti-Tax reactivity | :* A decreased level of anti-Tax reactivity | ||
Revision as of 17:32, 24 January 2016
- Common risk factors in the development of adult T-cell leukemia among HTLV carriers include:
- Vertical transmission of HTLV infection during infancy
- Male sex
- Specific human leukocyte antigens such as:
- Patients with a Strongyloides stercoralis co-infection
- An elevated soluble interleukin-2 receptor levels (> 500 U/ml)
- An elevated anti-HTLV-1 antibody titer
- An elevated HTLV proviral load level (> 4 copies per 100 peripheral blood mononuclear cells)
- An elevated WBC count (> 9,000/μL)
- An elevated abnormal lymphocyte count
- A decreased level of anti-Tax reactivity