Osteochondroma causes: Difference between revisions
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==Causes== | ==Causes== | ||
*There are no established direct causes for osteochondroma. | *There are no established direct causes for osteochondroma.<ref name="book">Osteochondromas/Osteocartilaginous exostosis." Wheeless Textbook of Anatomy, 1996. CR Wheeless. Duke University Medical Center</ref> | ||
*The development of hereditary multiple osteochondroma may be the result of multiple genetic mutations. | *The development of hereditary multiple osteochondroma may be the result of multiple genetic mutations.<ref name="pmid18853760">{{cite journal |vauthors=Kitsoulis P, Galani V, Stefanaki K, Paraskevas G, Karatzias G, Agnantis NJ, Bai M |title=Osteochondromas: review of the clinical, radiological and pathological features |journal=In Vivo (Athens, Greece) |volume=22 |issue=5 |pages=633–46 |year=2008 |pmid=18853760 |doi= |url=http://iv.iiarjournals.org/cgi/pmidlookup?view=long&pmid=18853760}}</ref> | ||
<ref name="pmid18853760">{{cite journal |vauthors=Kitsoulis P, Galani V, Stefanaki K, Paraskevas G, Karatzias G, Agnantis NJ, Bai M |title=Osteochondromas: review of the clinical, radiological and pathological features |journal=In Vivo (Athens, Greece) |volume=22 |issue=5 |pages=633–46 |year=2008 |pmid=18853760 |doi= |url=http://iv.iiarjournals.org/cgi/pmidlookup?view=long&pmid=18853760}}</ref> | |||
*Genetic mutations include: | *Genetic mutations include: | ||
:* | :*Germ line mutation EXT1 | ||
:* | :*Germ line mutation EXT2 | ||
==References== | ==References== |
Revision as of 16:59, 27 January 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
There are no established direct causes for osteochondroma. The development of hereditary multiple osteochondroma may be the result of multiple genetic mutations.[1]
Causes
- There are no established direct causes for osteochondroma.[2]
- The development of hereditary multiple osteochondroma may be the result of multiple genetic mutations.[1]
- Genetic mutations include:
- Germ line mutation EXT1
- Germ line mutation EXT2
References
- ↑ 1.0 1.1 Kitsoulis P, Galani V, Stefanaki K, Paraskevas G, Karatzias G, Agnantis NJ, Bai M (2008). "Osteochondromas: review of the clinical, radiological and pathological features". In Vivo (Athens, Greece). 22 (5): 633–46. PMID 18853760.
- ↑ Osteochondromas/Osteocartilaginous exostosis." Wheeless Textbook of Anatomy, 1996. CR Wheeless. Duke University Medical Center