Mycosis fungoides natural history, complications and prognosis: Difference between revisions

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==Overview==
==Overview==
If left untreated, cutaneous T cell lymphoma may progress to develop cutaneous patches and plaque., plaque, and tumors. Depending on the extent of the lymphoma at the time of diagnosis, the prognosis may vary.
If left untreated, cutaneous T cell lymphoma may progress to develop cutaneous patches and plaque., plaque, and tumors. Depending on the extent of the lymphoma at the time of diagnosis, the prognosis may vary.
==Natural history==
==Natural History==
* Mycosis fungoides is initially an indolent lymphoma that may later develop peripheral lymphadenopathy and can finally progress to widespread visceral involvement.<ref name=radio>Mycosis fungoides. Radiopaedia.http://radiopaedia.org/articles/mycosis-fungoides Accessed on January 20, 2016</ref>
* Mycosis fungoides is initially an indolent lymphoma that may later develop peripheral lymphadenopathy and can finally progress to widespread visceral involvement.<ref name=radio>Mycosis fungoides. Radiopaedia.http://radiopaedia.org/articles/mycosis-fungoides Accessed on January 20, 2016</ref>
* Cutaneous T cell lymphoma is usually initially seen by [[dermatologists]] with patients presenting with skin lesions
* Cutaneous T cell lymphoma is usually initially seen by dermatologists with patients presenting with skin lesions.
* Patients often have a history of several years of [[eczematous]] or dermatitic skin lesions before the diagnosis is finally established
* Patients often have a history of several years of eczematous or dermatitic skin lesions before the diagnosis is finally established.
* The skin lesions then progress from the patch stage to the [[plaque]] stage to cutaneous tumors
* The skin lesions then progress from the patch stage to the [[plaque]] stage to cutaneous tumors.
 
==Prognosis==
==Prognosis==
* Cutaneous T cell lymphoma is usually a slow-growing (indolent) lymphoma<ref name= canadiancancer> Cutaneous T cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/cutaneous-t-cell-lymphoma/?region=on Accessed on January 19, 2016</ref>
* Cutaneous T cell lymphoma is usually a slow-growing (indolent) lymphoma.<ref name= canadiancancer> Cutaneous T cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/cutaneous-t-cell-lymphoma/?region=on Accessed on January 19, 2016</ref>
* The prognosis for people with cutaneous T cell lymphoma is based on the extent of disease and how the person responds to treatment  
* The prognosis for people with cutaneous T cell lymphoma is based on the extent of disease and how the person responds to treatment.
* Although more advanced stages of cutaneous T cell lymphoma may not be cured, the lymphoma can still be controlled with treatment
* Although more advanced stages of cutaneous T cell lymphoma may not be cured, the lymphoma can still be controlled with treatment.
===Favorable prognosis===
===Favorable prognosis===
* Early stage disease
* Early stage disease

Revision as of 19:26, 27 January 2016

Cutaneous T cell lymphoma Microchapters

Home

Patient Information

Overview

Classification

Mycosis fungoides
Sezary syndrome

Pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

If left untreated, cutaneous T cell lymphoma may progress to develop cutaneous patches and plaque., plaque, and tumors. Depending on the extent of the lymphoma at the time of diagnosis, the prognosis may vary.

Natural History

  • Mycosis fungoides is initially an indolent lymphoma that may later develop peripheral lymphadenopathy and can finally progress to widespread visceral involvement.[1]
  • Cutaneous T cell lymphoma is usually initially seen by dermatologists with patients presenting with skin lesions.
  • Patients often have a history of several years of eczematous or dermatitic skin lesions before the diagnosis is finally established.
  • The skin lesions then progress from the patch stage to the plaque stage to cutaneous tumors.

Prognosis

  • Cutaneous T cell lymphoma is usually a slow-growing (indolent) lymphoma.[2]
  • The prognosis for people with cutaneous T cell lymphoma is based on the extent of disease and how the person responds to treatment.
  • Although more advanced stages of cutaneous T cell lymphoma may not be cured, the lymphoma can still be controlled with treatment.

Favorable prognosis

  • Early stage disease
  • Lymphoma is confined to the skin

Unfavorable prognosis

  • More advanced disease
  • Lymphoma has spread to lymph nodes
  • Lymphoma has spread to other organs

References

  1. Mycosis fungoides. Radiopaedia.http://radiopaedia.org/articles/mycosis-fungoides Accessed on January 20, 2016
  2. Cutaneous T cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/cutaneous-t-cell-lymphoma/?region=on Accessed on January 19, 2016


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