Osteochondroma causes: Difference between revisions
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{{Osteochondroma}} | {{Osteochondroma}} | ||
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==Overview== | ==Overview== | ||
There are no established direct causes for osteochondroma. The development of hereditary multiple osteochondroma may be the result of multiple genetic mutations.<ref name="pmid18853760">{{cite journal |vauthors=Kitsoulis P, Galani V, Stefanaki K, Paraskevas G, Karatzias G, Agnantis NJ, Bai M |title=Osteochondromas: review of the clinical, radiological and pathological features |journal=In Vivo (Athens, Greece) |volume=22 |issue=5 |pages=633–46 |year=2008 |pmid=18853760 |doi= |url=http://iv.iiarjournals.org/cgi/pmidlookup?view=long&pmid=18853760}}</ref> | There are no established direct causes for osteochondroma. The development of hereditary multiple osteochondroma may be the result of multiple genetic mutations.<ref name="pmid18853760">{{cite journal |vauthors=Kitsoulis P, Galani V, Stefanaki K, Paraskevas G, Karatzias G, Agnantis NJ, Bai M |title=Osteochondromas: review of the clinical, radiological and pathological features |journal=In Vivo (Athens, Greece) |volume=22 |issue=5 |pages=633–46 |year=2008 |pmid=18853760 |doi= |url=http://iv.iiarjournals.org/cgi/pmidlookup?view=long&pmid=18853760}}</ref> |
Revision as of 15:40, 29 January 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
There are no established direct causes for osteochondroma. The development of hereditary multiple osteochondroma may be the result of multiple genetic mutations.[1]
Causes
- There are no established direct causes for osteochondroma.[2]
- The development of hereditary multiple osteochondroma may be the result of multiple genetic mutations.[1]
- The related genetic mutations, include:[3]
- Germ line mutation in EXT1 gene located on chromosome 8q24.11-q24.13
- Germ line mutation in EXT2 gene located on chromosome 11p11-12
References
- ↑ 1.0 1.1 Kitsoulis P, Galani V, Stefanaki K, Paraskevas G, Karatzias G, Agnantis NJ, Bai M (2008). "Osteochondromas: review of the clinical, radiological and pathological features". In Vivo (Athens, Greece). 22 (5): 633–46. PMID 18853760.
- ↑ Osteochondromas/Osteocartilaginous exostosis." Wheeless Textbook of Anatomy, 1996. CR Wheeless. Duke University Medical Center
- ↑ Judith VMG Bovée. Multiple Osteochondromas: Review. Orphanet Journal of Rare Diseases. Biomed Central http://ojrd.biomedcentral.com/articles/10.1186/1750-1172-3-3 Accessed on January 27, 2016