Extramammary Paget's disease classification: Difference between revisions
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==Overview== | ==Overview== | ||
Extramammary Paget's disease may be classified into four subtypes based on site of origin and area affected. | |||
==Classification== | ==Classification== | ||
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The classification of extramammary Paget's disease is shown below in a tabular form: | |||
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*The majority of cases of vulval extramammary Paget's disease are primary; that is, arising within the epidermis, and very few are associated with cutaneous sweat gland tumors. | *The majority of cases of vulval extramammary Paget's disease are primary; that is, arising within the epidermis, and very few are associated with cutaneous sweat gland tumors. | ||
*In cases where there is a prominent dermal invasive component, it may be impossible to prove the primary site of origin of the | *In cases where there is a prominent dermal invasive component, it may be impossible to prove the primary site of origin of the tumor. | ||
*A new variant of “mammary like” cutaneous glands, which combines morphological features of eccrine, mammary, and apocrine glands, and occurs predominantly in the interlabial sulcus on the vulva, has also been proposed as the site of origin of sweat gland derived tumors from which extramammary Paget's disease arises. | *A new variant of “mammary like” cutaneous glands, which combines morphological features of eccrine, mammary, and apocrine glands, and occurs predominantly in the interlabial sulcus on the vulva, has also been proposed as the site of origin of sweat gland derived tumors from which extramammary Paget's disease arises. | ||
*Vulval extramammary Paget's disease has been described in association with endocervical, endometrial, vaginal, vulval (eg., Bartholin's gland), urethral, and bladder neoplasms. | *Vulval extramammary Paget's disease has been described in association with endocervical, endometrial, vaginal, vulval (eg., Bartholin's gland), urethral, and bladder neoplasms. |
Revision as of 16:42, 29 January 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Extramammary Paget's disease may be classified into four subtypes based on site of origin and area affected.
Classification
The classification of extramammary Paget's disease is shown below in a tabular form:
Type of Extramammary Paget's Disease | Description |
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References
- ↑ Curtin JP, Rubin SC, Jones WB, Hoskins WJ, Lewis JL (1990). "Paget's disease of the vulva". Gynecol Oncol. 39 (3): 374–7. PMID 2175288.
- ↑ Goldblum JR, Hart WR (1997). "Vulvar Paget's disease: a clinicopathologic and immunohistochemical study of 19 cases". Am J Surg Pathol. 21 (10): 1178–87. PMID 9331290.
- ↑ Fanning J, Lambert HC, Hale TM, Morris PC, Schuerch C (1999). "Paget's disease of the vulva: prevalence of associated vulvar adenocarcinoma, invasive Paget's disease, and recurrence after surgical excision". Am J Obstet Gynecol. 180 (1 Pt 1): 24–7. PMID 9914572.
- ↑ van der Putte SC (1991). "Anogenital "sweat" glands. Histology and pathology of a gland that may mimic mammary glands". Am J Dermatopathol. 13 (6): 557–67. PMID 1666822.
- ↑ van der Putte SC, van Gorp LH (1994). "Adenocarcinoma of the mammary-like glands of the vulva: a concept unifying sweat gland carcinoma of the vulva, carcinoma of supernumerary mammary glands and extramammary Paget's disease". J Cutan Pathol. 21 (2): 157–63. PMID 8040464.
- ↑ 6.0 6.1 Powell FC, Bjornsson J, Doyle JA, Cooper AJ (1985). "Genital Paget's disease and urinary tract malignancy". J Am Acad Dermatol. 13 (1): 84–90. PMID 2993379.
- ↑ 7.0 7.1 Koga F, Gotoh S, Suzuki S (1997). "[A case of invasive bladder cancer with Pagetoid skin lesion of the vulva and anogenital Paget's disease]". Nihon Hinyokika Gakkai Zasshi. 88 (4): 503–6. PMID 9155118.
- ↑ Hayashibara Y, Ikeda S (1988). "[Extramammary Paget's disease with internal malignancies]". Gan To Kagaku Ryoho. 15 (4 Pt 2-3): 1569–75. PMID 2837997.
- ↑ Nakano S, Narita R, Tabaru A, Ogami Y, Otsuki M (1995). "Bile duct cancer associated with extramammary Paget's disease". Am J Gastroenterol. 90 (3): 507–8. PMID 7872301.
- ↑ Popiolek DA, Hajdu SI, Gal D (1998). "Synchronous Paget's disease of the vulva and breast". Gynecol Oncol. 71 (1): 137–40. doi:10.1006/gyno.1998.5136. PMID 9784335.
- ↑ Goldblum JR, Hart WR (1998). "Perianal Paget's disease: a histologic and immunohistochemical study of 11 cases with and without associated rectal adenocarcinoma". Am J Surg Pathol. 22 (2): 170–9. PMID 9500217.
- ↑ Allan SJ, McLaren K, Aldridge RD (1998). "Paget's disease of the scrotum: a case exhibiting positive prostate-specific antigen staining and associated prostatic adenocarcinoma". Br J Dermatol. 138 (4): 689–91. PMID 9640381.