11β-hydroxylase deficiency laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of congenital adrenal hyperplasia due to 11β-hydroxylase deficiency include elevated 17α-hydroxyprogesterone, elevated androstenedione, elevated urinary 17-ketosteroids and decreased renin. | Laboratory findings consistent with the diagnosis of congenital adrenal hyperplasia due to 11β-hydroxylase deficiency include elevated 17α-hydroxyprogesterone, elevated androstenedione, elevated urinary 17-ketosteroids and decreased renin.<ref name="AlqahtaniShati2015">{{cite journal|last1=Alqahtani|first1=Mohammad A.|last2=Shati|first2=Ayed A.|last3=Zou|first3=Minjing|last4=Alsuheel|first4=Ali M.|last5=Alhayani|first5=Abdullah A.|last6=Al-Qahtani|first6=Saleh M.|last7=Gilban|first7=Hessa M.|last8=Meyer|first8=Brain F.|last9=Shi|first9=Yufei|title=A Novel Mutation in theCYP11B1Gene Causes Steroid 11β-Hydroxylase Deficient Congenital Adrenal Hyperplasia with Reversible Cardiomyopathy|journal=International Journal of Endocrinology|volume=2015|year=2015|pages=1–5|issn=1687-8337|doi=10.1155/2015/595164}}</ref> | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
* Elevated serum levels of 11-deoxycorticosterone<ref name="AlqahtaniShati2015">{{cite journal|last1=Alqahtani|first1=Mohammad A.|last2=Shati|first2=Ayed A.|last3=Zou|first3=Minjing|last4=Alsuheel|first4=Ali M.|last5=Alhayani|first5=Abdullah A.|last6=Al-Qahtani|first6=Saleh M.|last7=Gilban|first7=Hessa M.|last8=Meyer|first8=Brain F.|last9=Shi|first9=Yufei|title=A Novel Mutation in theCYP11B1Gene Causes Steroid 11β-Hydroxylase Deficient Congenital Adrenal Hyperplasia with Reversible Cardiomyopathy|journal=International Journal of Endocrinology|volume=2015|year=2015|pages=1–5|issn=1687-8337|doi=10.1155/2015/595164}}</ref> | * Elevated serum levels of 11-deoxycorticosterone<ref name="AlqahtaniShati2015">{{cite journal|last1=Alqahtani|first1=Mohammad A.|last2=Shati|first2=Ayed A.|last3=Zou|first3=Minjing|last4=Alsuheel|first4=Ali M.|last5=Alhayani|first5=Abdullah A.|last6=Al-Qahtani|first6=Saleh M.|last7=Gilban|first7=Hessa M.|last8=Meyer|first8=Brain F.|last9=Shi|first9=Yufei|title=A Novel Mutation in theCYP11B1Gene Causes Steroid 11β-Hydroxylase Deficient Congenital Adrenal Hyperplasia with Reversible Cardiomyopathy|journal=International Journal of Endocrinology|volume=2015|year=2015|pages=1–5|issn=1687-8337|doi=10.1155/2015/595164}}</ref> | ||
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* Decreased renin | * Decreased renin | ||
==References== | ==References== | ||
{{Reflist| | {{Reflist|1}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
Revision as of 18:35, 7 February 2016
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Congenital adrenal hyperplasia due to 11β-hydroxylase deficiency Microchapters |
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Differentiating Congenital adrenal hyperplasia due to 11β-hydroxylase deficiency from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Laboratory findings consistent with the diagnosis of congenital adrenal hyperplasia due to 11β-hydroxylase deficiency include elevated 17α-hydroxyprogesterone, elevated androstenedione, elevated urinary 17-ketosteroids and decreased renin.[1]
Laboratory Findings
- Elevated serum levels of 11-deoxycorticosterone[1]
- Elevated 17α-hydroxyprogesterone
- Elevated androstenedione
- Elevated urinary 17-ketosteroids
- Elevated urinary tetra hydrometabolites
- Decreased cortisol
- Decreased aldosterone
- Decreased renin
References
- ↑ 1.0 1.1 Alqahtani, Mohammad A.; Shati, Ayed A.; Zou, Minjing; Alsuheel, Ali M.; Alhayani, Abdullah A.; Al-Qahtani, Saleh M.; Gilban, Hessa M.; Meyer, Brain F.; Shi, Yufei (2015). "A Novel Mutation in theCYP11B1Gene Causes Steroid 11β-Hydroxylase Deficient Congenital Adrenal Hyperplasia with Reversible Cardiomyopathy". International Journal of Endocrinology. 2015: 1–5. doi:10.1155/2015/595164. ISSN 1687-8337.