Sandbox: Langerhans: Difference between revisions
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* Langerhans cell histiocytosis is a rare disease that tends to affect children and adolescents. | * Langerhans cell histiocytosis is a rare disease that tends to affect children and adolescents.<ref name="pmid25281259">{{cite journal| author=DiCaprio MR, Roberts TT| title=Diagnosis and Management of Langerhans Cell Histiocytosis. | journal=J Am Acad Orthop Surg | year= 2014 | volume= 22 | issue= 10 | pages= 643-652 | pmid=25281259 | doi=10.5435/JAAOS-22-10-643 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25281259 }} </ref> | ||
* The incidence of Langerhans cell histiocytosis is approximately 5 per 1,000,000 individuals in the United States. | * The incidence of Langerhans cell histiocytosis is approximately 5 per 1,000,000 individuals in the United States. | ||
* Langerhans cell histiocytosis commonly affects individuals younger than 15 years of age. | * Langerhans cell histiocytosis commonly affects individuals younger than 15 years of age. | ||
Revision as of 15:20, 4 February 2016
LCH is a rare disease,
- Langerhans cell histiocytosis is a rare disease that tends to affect children and adolescents.[1]
- The incidence of Langerhans cell histiocytosis is approximately 5 per 1,000,000 individuals in the United States.
- Langerhans cell histiocytosis commonly affects individuals younger than 15 years of age.
- The median age at diagnosis is depends on the specific subtype of the disease, such as:
- Pulmonary Langerhans cell histiocytosis is usually first diagnosed among adults.
- Unifocal Langerhans cell histiocytosis and multifocal unisystem Langerhans cell histiocytosis are usually first diagnosed among individuals of 2-10 years of age.
- Multifocal multisystem Langerhans cell histiocytosis is usually first diagnosed among individuals younger than 2 years of age.
- Males are more commonly affected with Langerhans cell histiocytosis than females. The male to female ratio is approximately 2 to 1.
- ↑ DiCaprio MR, Roberts TT (2014). "Diagnosis and Management of Langerhans Cell Histiocytosis". J Am Acad Orthop Surg. 22 (10): 643–652. doi:10.5435/JAAOS-22-10-643. PMID 25281259.