Sandbox: Langerhans: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
* Several cellular markers have been associated with poor disease prognosis, including expression of certain metalloproteinases and gelosin, a regulatory protein involved in the disassembly of actin microfilaments.41 Other factors for poor prognosis include extensive organ involvement and younger patient age at diagnosis.8 Younger age at diagnosis is associated with multisystem disease. | |||
* The table below lists prognostic factors for Langerhans cell histiocytosis patients: | * The table below lists prognostic factors for Langerhans cell histiocytosis patients: | ||
{| style="border: 0px; font-size: 90%; margin: 3px; width: 1000px" | {| style="border: 0px; font-size: 90%; margin: 3px; width: 1000px" |
Revision as of 16:22, 4 February 2016
- Several cellular markers have been associated with poor disease prognosis, including expression of certain metalloproteinases and gelosin, a regulatory protein involved in the disassembly of actin microfilaments.41 Other factors for poor prognosis include extensive organ involvement and younger patient age at diagnosis.8 Younger age at diagnosis is associated with multisystem disease.
- The table below lists prognostic factors for Langerhans cell histiocytosis patients:
Prognostic Factor | Description |
---|---|
Age |
|
Gender |
|
Performance status |
|
Stage |
|
Lymphocyte doubling time |
|
Genetic mutations |
|
Prolymphocytes percent |
|
Histological analysis |
|
Lactate dehydrogenase (LDH) level |
|
β2-microglobulin level |
|
Lymphocyte surface markers |
|
Immunoglobulin (Ig)VH gene |
|
Membrane-bound proteins |
|