Brucellosis primary prevention: Difference between revisions
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==Overview== | ==Overview== | ||
Effective measures for the [[primary prevention]] of brucellosis include not consuming unpasteurized [[Dairy product|dairy]] or undercooked meat, and having safe occupational practices. There are no available [[vaccines]] for [[Human|humans]] against brucellosis.<ref name=" | Effective measures for the [[primary prevention]] of brucellosis include not consuming unpasteurized [[Dairy product|dairy]] or undercooked meat, and having safe occupational practices. There are no available [[vaccines]] for [[Human|humans]] against brucellosis.<ref name="j">Brucellosis. CDC. http://www.cdc.gov/brucellosis/prevention/index.html. Accessed on February 5, 2016</ref><ref name="a">Brucellosis. Wikipedia. https://en.wikipedia.org/wiki/Brucellosis. Accessed on February 5, 2016</ref> | ||
==Prevention== | ==Prevention== | ||
| Line 40: | Line 40: | ||
***The recent [[transmission]] of brucellosis from elk back to cattle in Idaho and Wyoming illustrates how the area, as the last remaining reservoir in the United States, may adversely affect the livestock industry. | ***The recent [[transmission]] of brucellosis from elk back to cattle in Idaho and Wyoming illustrates how the area, as the last remaining reservoir in the United States, may adversely affect the livestock industry. | ||
***Eliminating brucellosis from this area is a challenge, as many viewpoints exist on how to manage diseased [[wildlife]]. | ***Eliminating brucellosis from this area is a challenge, as many viewpoints exist on how to manage diseased [[wildlife]]. | ||
***Purebred bison in the Henry Mountains of southern Utah are free of brucellosis.<ref name=" | ***Purebred bison in the Henry Mountains of southern Utah are free of brucellosis.<ref name=""j">Brucellosis. CDC. http://www.cdc.gov/brucellosis/prevention/index.html. Accessed on February 5, 2016</ref><ref name="a">Brucellosis. Wikipedia. https://en.wikipedia.org/wiki/Brucellosis. Accessed on February 5, 2016</ref> | ||
==Vaccines== | ==Vaccines== | ||
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**Accidental [[human]] exposure to RB51, though uncommon, has resulted in development of [[symptoms]] consistent with brucellosis. | **Accidental [[human]] exposure to RB51, though uncommon, has resulted in development of [[symptoms]] consistent with brucellosis. | ||
**Exposures have included needle sticks, [[eye]] and wound splashes, and contact with [[infected]] material. | **Exposures have included needle sticks, [[eye]] and wound splashes, and contact with [[infected]] material. | ||
*Other [[vaccines]], such as [[Brucella abortus|''Brucella abortus'']] S19 for cattle and ''[[Brucella melitensis|B. melitensis]]'' Rev-1 for sheep and goats, can also cause [[infection]] in [[humans]].<ref name=" | *Other [[vaccines]], such as [[Brucella abortus|''Brucella abortus'']] S19 for cattle and ''[[Brucella melitensis|B. melitensis]]'' Rev-1 for sheep and goats, can also cause [[infection]] in [[humans]].<ref name="k">Brucellosis. CDC. http://www.cdc.gov/brucellosis/veterinarians/cattle.html. Accessed on February 5, 2016</ref> | ||
==Reference== | ==Reference== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Bacterial diseases]] | [[Category:Bacterial diseases]] | ||
[[Category:Occupational diseases]] | [[Category:Occupational diseases]] | ||
Revision as of 19:52, 5 February 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Danitza Lukac
Overview
Effective measures for the primary prevention of brucellosis include not consuming unpasteurized dairy or undercooked meat, and having safe occupational practices. There are no available vaccines for humans against brucellosis.[1][2]
Prevention
- The best way to prevent brucellosis infection is to be sure you do not consume:
- Undercooked meat
- Unpasteurized dairy products, including:
- Milk
- Cheese
- Ice cream
- Pasteurization is when raw milk is heated to a high temperature for a short period of time. This heating process destroys harmful bacteria that may make the milk unsafe to consume.
- If you are not sure that the dairy product is pasteurized, do not eat it.
- People who handle animal tissues (such as hunters and animal herdsman) should protect themselves by using:
- Recommendations for Safe Laboratory Practices:
- When brucellosis is suspected in a patient, clinicians should not "suspect or rule out brucellosis" on the laboratory submission.
- Review laboratory containment methods and microbiological procedures to ensure compliance with recommendations in the Biosafety in Microbiological and Biomedical Laboratories (BMBL) 5th Edition
- Use primary barriers: use safety centrifuge cups, personal protective equipment, and class II or higher Biological Safety Cabinets (BSCs) for procedures with a high likelihood of producing droplet splashes or aerosols.
- Use secondary barriers: restrict access to the laboratory when work is being performed and maintain the integrity of the laboratory's air handling system by keeping external doors and windows closed.
- Perform all procedures on unidentified isolates carefully to minimize the creation of splashes or aerosols.
- Prohibit sniffing of opened culture plates to assist in the identification of isolates. Manipulate isolates of small gram-negative or gram-variable rods within a BSC.
- USA:
- Dairy herds in the USA to be certified brucellosis-free are tested at least once a year with the Brucella milk ring test.
- Cows confirmed to be infected are often killed.
- In the United States, veterinarians are required to vaccinate all young stock, thereby further reducing the chance of zoonotic transmission.
- This vaccination is usually referred to as a "calfhood" vaccination.
- Most cattle receive a tattoo in one of their ears, serving as proof of their vaccination status.
- The first state–federal cooperative efforts towards eradication of brucellosis caused by Brucella abortus in the U.S. began in 1934.
- Wild bison and elk in the greater Yellowstone area are the last remaining reservoir of B. abortus in the US.
- The recent transmission of brucellosis from elk back to cattle in Idaho and Wyoming illustrates how the area, as the last remaining reservoir in the United States, may adversely affect the livestock industry.
- Eliminating brucellosis from this area is a challenge, as many viewpoints exist on how to manage diseased wildlife.
- Purebred bison in the Henry Mountains of southern Utah are free of brucellosis.[3][2]
Vaccines
- There are no available vaccines for humans against brucellosis.
- B. abortus RB51 is a strain of this bacterium developed specifically for immunization of cattle against brucellosis to allow serological differentiation between naturally infected and vaccinated animals.
- Other vaccines, such as Brucella abortus S19 for cattle and B. melitensis Rev-1 for sheep and goats, can also cause infection in humans.[4]
Reference
- ↑ Brucellosis. CDC. http://www.cdc.gov/brucellosis/prevention/index.html. Accessed on February 5, 2016
- ↑ 2.0 2.1 Brucellosis. Wikipedia. https://en.wikipedia.org/wiki/Brucellosis. Accessed on February 5, 2016
- ↑ Brucellosis. CDC. http://www.cdc.gov/brucellosis/prevention/index.html. Accessed on February 5, 2016
- ↑ Brucellosis. CDC. http://www.cdc.gov/brucellosis/veterinarians/cattle.html. Accessed on February 5, 2016