Trichinosis medical therapy: Difference between revisions
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=== Treatment for asymptomatic, abortive and mild patients: === | === Treatment for asymptomatic, abortive and mild patients: === | ||
*Administration of [[Anthelmintic|anthelmintics]] | |||
*Administration of [[glucocorticoids]] if needed. | |||
=== Treatment for pronounced and severe patients: === | === Treatment for pronounced and severe patients: === | ||
*[[Hospitalization]] | |||
**Compulsory for severe cases | |||
*Administration of [[glucocorticoids]], [[Anthelmintic|anthelmintics]] and [[analgesics]]. | |||
*Administration of fluids and [[Electrolyte|electrolytes]] <ref name="pmid19136437">{{cite journal| author=Gottstein B, Pozio E, Nöckler K| title=Epidemiology, diagnosis, treatment, and control of trichinellosis. | journal=Clin Microbiol Rev | year= 2009 | volume= 22 | issue= 1 | pages= 127-45, Table of Contents | pmid=19136437 | doi=10.1128/CMR.00026-08 | pmc=PMC2620635 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19136437 }} </ref> | |||
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* | * | ||
*Both drugs are considered relatively safe but have been associated with side effects including [[bone marrow suppression]]. | |||
*Both | |||
*Patients on longer courses of therapy should be monitored by serial [[complete blood counts]] to detect any [[adverse effects]] promptly and discontinue treatment. | *Patients on longer courses of therapy should be monitored by serial [[complete blood counts]] to detect any [[adverse effects]] promptly and discontinue treatment. | ||
*[[Albendazole]] and [[mebendazole]] are not approved for use in | *[[Albendazole]] and [[mebendazole]] are not approved for use in pregnant women or children under the age of 2 years. | ||
*In addition to [[Antiparasitic|antiparasitic medication]], treatment with [[glucocorticoids]] such as [[prednisone]] may be used to relieve [[muscle pain]] associated with larval migration.<ref name="d">Trichinellosis. CDC. http://www.cdc.gov/parasites/trichinellosis/health_professionals/index.html#tx. Accessed on January 26, 2016</ref> | *In addition to [[Antiparasitic|antiparasitic medication]], treatment with [[glucocorticoids]] such as [[prednisone]] may be used to relieve [[muscle pain]] associated with larval migration.<ref name="d">Trichinellosis. CDC. http://www.cdc.gov/parasites/trichinellosis/health_professionals/index.html#tx. Accessed on January 26, 2016</ref> | ||
Revision as of 20:04, 8 February 2016
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Trichinosis Microchapters |
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Treatment |
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Trichinosis medical therapy On the Web |
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American Roentgen Ray Society Images of Trichinosis medical therapy |
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Risk calculators and risk factors for Trichinosis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Danitza Lukac
Overview
The mainstay of therapy for trichinosis are anthelmintics drugs such as albendazole or mebendazole.[1]
Medical Therapy
Treatment for asymptomatic, abortive and mild patients:
- Administration of anthelmintics
- Administration of glucocorticoids if needed.
Treatment for pronounced and severe patients:
- Hospitalization
- Compulsory for severe cases
- Administration of glucocorticoids, anthelmintics and analgesics.
- Administration of fluids and electrolytes [2]
| Drug | Adult and Pediatric Dose |
|---|---|
| Albendazole | 400 mg twice a day by mouth for 8 to 14 days |
| Mebendazole | 200 to 400 mg three times a day by mouth for 3 days, then 400 to 500 mg three times a day by mouth for 10 days |
- Both drugs are considered relatively safe but have been associated with side effects including bone marrow suppression.
- Patients on longer courses of therapy should be monitored by serial complete blood counts to detect any adverse effects promptly and discontinue treatment.
- Albendazole and mebendazole are not approved for use in pregnant women or children under the age of 2 years.
- In addition to antiparasitic medication, treatment with glucocorticoids such as prednisone may be used to relieve muscle pain associated with larval migration.[1]
References
- ↑ 1.0 1.1 Trichinellosis. CDC. http://www.cdc.gov/parasites/trichinellosis/health_professionals/index.html#tx. Accessed on January 26, 2016
- ↑ Gottstein B, Pozio E, Nöckler K (2009). "Epidemiology, diagnosis, treatment, and control of trichinellosis". Clin Microbiol Rev. 22 (1): 127–45, Table of Contents. doi:10.1128/CMR.00026-08. PMC 2620635. PMID 19136437.