Brucellosis diagnostic criteria: Difference between revisions
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==Diagnostic Criteria== | ==Diagnostic Criteria== | ||
=== '''Clinical Description''' === | === '''Clinical Description'''<ref name="e">Brucellosis 2010 Case Definition. CDC. http://wwwn.cdc.gov/nndss/conditions/brucellosis/case-definition/2010/. Accessed on February 2, 2016</ref> === | ||
*An illness characterized by acute or insidious onset of [[fever]] and one or more of the following: | *An illness characterized by acute or insidious onset of [[fever]] and one or more of the following: | ||
**[[Night sweats]] | **[[Night sweats]] | ||
| Line 37: | Line 37: | ||
=== Confirmed === | === Confirmed === | ||
*A clinically compatible illness with definitive laboratory evidence of [[Brucella|''Brucella'']] infection | *A clinically compatible illness with definitive laboratory evidence of [[Brucella|''Brucella'']] infection | ||
==Reference== | ==Reference== | ||
Revision as of 13:54, 9 February 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Danitza Lukac
Overview
The diagnosis of brucellosis is based on clinical and laboratory criteria.[1]
Diagnostic Criteria
Clinical Description[1]
- An illness characterized by acute or insidious onset of fever and one or more of the following:
- Night sweats
- Arthralgia
- Headache
- Fatigue
- Anorexia
- Myalgia
- Weight loss
- Arthritis/spondylitis
- Meningitis
- Focal organ involvement (endocarditis, orchitis/epididymitis, hepatomegaly, splenomegaly)
Laboratory Criteria for Diagnosis
- Definitive:
- Culture and identification of Brucella spp. from clinical specimens
- Evidence of a fourfold or greater rise in Brucella antibody titer between acute- and convalescent-phase serum specimens obtained greater than or equal to 2 weeks apart
- Presumptive:
Case Classification
Probable
- A clinically compatible illness with at least one of the following:
- Epidemiologically linked to a confirmed human or animal brucellosis case
- Presumptive laboratory evidence, but without definitive laboratory evidence, of Brucella infection
Confirmed
- A clinically compatible illness with definitive laboratory evidence of Brucella infection
Reference
- ↑ 1.0 1.1 Brucellosis 2010 Case Definition. CDC. http://wwwn.cdc.gov/nndss/conditions/brucellosis/case-definition/2010/. Accessed on February 2, 2016