Brucellosis diagnostic criteria: Difference between revisions
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==Diagnostic Criteria== | ==Diagnostic Criteria== | ||
{| class="wikitable" | |||
! colspan="2" |Diagnosis of brucellosis | |||
|- | |||
|History of potential exposure | |||
| | |||
|- | |||
|presentation consistent with the disease | |||
|An illness characterized by acute or insidious onset of [[fever]] and one or more of the following: | |||
*[[Night sweats]] | |||
*[[Arthralgia]] | |||
*[[Headache]] | |||
*[[Fatigue]] | |||
*[[Anorexia]] | |||
*[[Myalgia]] | |||
*[[Weight loss]] | |||
*[[Arthritis]]/[[spondylitis]] | |||
*[[Meningitis]] | |||
*Focal organ involvement ([[endocarditis]], [[orchitis]]/[[epididymitis]], [[hepatomegaly]], [[splenomegaly]]) | |||
|- | |||
|Supporting laboratory findings | |||
| | |||
*'''Definitive:''' | *'''Definitive:''' | ||
**Culture and identification of [[Brucella|''Brucella spp'']]. from clinical specimens | **Culture and identification of [[Brucella|''Brucella spp'']]. from clinical specimens | ||
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**[[Brucella|''Brucella'']] total antibody titer of greater than or equal to 160 by standard tube agglutination test (SAT) or [[Brucella|''Brucella'']] microagglutination test (BMAT) in one or more serum specimens obtained after onset of symptoms | **[[Brucella|''Brucella'']] total antibody titer of greater than or equal to 160 by standard tube agglutination test (SAT) or [[Brucella|''Brucella'']] microagglutination test (BMAT) in one or more serum specimens obtained after onset of symptoms | ||
**Detection of [[Brucella|''Brucella'']] DNA in a clinical specimen by PCR assay | **Detection of [[Brucella|''Brucella'']] DNA in a clinical specimen by PCR assay | ||
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** | |||
== '''Case Classification''' == | == '''Case Classification''' == | ||
Revision as of 21:16, 4 January 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Danitza Lukac
Overview
The diagnosis of brucellosis is based on clinical and laboratory criteria.[1]
Diagnostic Criteria
| Diagnosis of brucellosis | |
|---|---|
| History of potential exposure | |
| presentation consistent with the disease | An illness characterized by acute or insidious onset of fever and one or more of the following:
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| Supporting laboratory findings |
|
Case Classification
Probable
- A clinically compatible illness with at least one of the following:
- Epidemiologically linked to a confirmed human or animal brucellosis case
- Presumptive laboratory evidence, but without definitive laboratory evidence, of Brucella infection
Confirmed
- A clinically compatible illness with definitive laboratory evidence of Brucella infection
Reference
- ↑ Brucellosis 2010 Case Definition. CDC. http://wwwn.cdc.gov/nndss/conditions/brucellosis/case-definition/2010/. Accessed on February 2, 2016