Primary central nervous system lymphoma CT: Difference between revisions
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==CT== | ==CT== | ||
Head CT scan may be helpful in the diagnosis of primary central nervous system lymphoma. Findings on CT scan suggestive of primary central nervous system lymphoma include:<ref name=radiographicfeaturesofprimarycnslymphoma1>Radiographic features of primary CNS lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref> | *Head CT scan may be helpful in the diagnosis of primary central nervous system lymphoma. Findings on CT scan suggestive of primary central nervous system lymphoma include:<ref name=radiographicfeaturesofprimarycnslymphoma1>Radiographic features of primary CNS lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref> | ||
*[[Supratentorial|Supratentorial mass]] with subependymal extension | :*[[Supratentorial|Supratentorial mass]] with subependymal extension | ||
*Crossing the [[corpus callosum]] observed frequently | :*Crossing the [[corpus callosum]] observed frequently | ||
*Lesions are hyperattenuating (70%) | :*Lesions are hyperattenuating (70%) | ||
*Enhancement present | :*Enhancement present | ||
*[[Hemorrhage]] is distinctly present | :*[[Hemorrhage]] is distinctly present | ||
*Multiple lesions in patients with HIV/AIDS | :*Multiple lesions in patients with HIV/AIDS | ||
*Enhancement on both CT scan and MRI is pronounced and usually '''homogeneous'''. Even with larger lesions, there is little mass effect for size and limited surrounding vasogenic [[edema]]. | |||
*Low grade tumors differ from the more common high-grade primary central nervous system lymphoma in several ways:<ref name=radiographicfeaturesofprimarycnslymphoma1>Radiographic features of primary CNS lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref> | |||
:*Deep locations and spinal involvement is more common | |||
:*Contrast enhancement is absent, irregular, or only mild | |||
*Disseminated meningeal/intraventricular disease is uncommon, it is observed in ~5% of cases at presentation and usually in high grade cases.<ref name=radiographicfeaturesofprimarycnslymphoma1>Radiographic features of primary CNS lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref> | |||
*It should be noted that in patients who are immunocompromised (typically HIV/AIDS or post-transplant), enhancement is more heterogeneous.<ref name=radiographicfeaturesofprimarycnslymphoma1>Radiographic features of primary CNS lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref> | |||
==References== | ==References== | ||
Revision as of 15:23, 18 February 2016
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Primary central nervous system lymphoma Microchapters |
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Differentiating Primary Central Nervous System Lymphoma from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Primary central nervous system lymphoma CT On the Web |
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American Roentgen Ray Society Images of Primary central nervous system lymphoma CT |
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Directions to Hospitals Treating Primary central nervous system lymphoma |
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Risk calculators and risk factors for Primary central nervous system lymphoma CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
CT
- Head CT scan may be helpful in the diagnosis of primary central nervous system lymphoma. Findings on CT scan suggestive of primary central nervous system lymphoma include:[1]
- Supratentorial mass with subependymal extension
- Crossing the corpus callosum observed frequently
- Lesions are hyperattenuating (70%)
- Enhancement present
- Hemorrhage is distinctly present
- Multiple lesions in patients with HIV/AIDS
- Enhancement on both CT scan and MRI is pronounced and usually homogeneous. Even with larger lesions, there is little mass effect for size and limited surrounding vasogenic edema.
- Low grade tumors differ from the more common high-grade primary central nervous system lymphoma in several ways:[1]
- Deep locations and spinal involvement is more common
- Contrast enhancement is absent, irregular, or only mild
- Disseminated meningeal/intraventricular disease is uncommon, it is observed in ~5% of cases at presentation and usually in high grade cases.[1]
- It should be noted that in patients who are immunocompromised (typically HIV/AIDS or post-transplant), enhancement is more heterogeneous.[1]
References
- ↑ 1.0 1.1 1.2 1.3 Radiographic features of primary CNS lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016