Primary central nervous system lymphoma CT: Difference between revisions
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==Overview== | ==Overview== | ||
==CT== | ==Head CT== | ||
*Head CT scan may be helpful in the diagnosis of primary central nervous system lymphoma. Findings on CT scan suggestive of primary central nervous system lymphoma include:<ref name=radiographicfeaturesofprimarycnslymphoma1>Radiographic features of primary CNS lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref> | *Head CT scan may be helpful in the diagnosis of primary central nervous system lymphoma. Findings on CT scan suggestive of primary central nervous system lymphoma include:<ref name=radiographicfeaturesofprimarycnslymphoma1>Radiographic features of primary CNS lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref> | ||
:*[[Supratentorial|Supratentorial mass]] with subependymal extension | :*[[Supratentorial|Supratentorial mass]] with subependymal extension | ||
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*It should be noted that in patients who are immunocompromised (typically HIV/AIDS or post-transplant), enhancement is more heterogeneous.<ref name=radiographicfeaturesofprimarycnslymphoma1>Radiographic features of primary CNS lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref> | *It should be noted that in patients who are immunocompromised (typically HIV/AIDS or post-transplant), enhancement is more heterogeneous.<ref name=radiographicfeaturesofprimarycnslymphoma1>Radiographic features of primary CNS lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref> | ||
==Gallery== | ===Gallery=== | ||
<gallery> | <gallery> | ||
Image:Ct image primary central nervous system lymphoma image 1.jpg|<sub>Single image from a non-contrast CT scan demonstrating a vague bilateral hyperdensity crossing the midline.<ref name=ctimage1>Image courtesy of Dr. Frank Gaillard. Radiopaedia (original file [http://radiopaedia.org/cases/cns-lymphoma-primary here]). Creative Commons BY-SA-NC</ref></sub></gallery> | Image:Ct image primary central nervous system lymphoma image 1.jpg|<sub>Single image from a non-contrast CT scan demonstrating a vague bilateral hyperdensity crossing the midline.<ref name=ctimage1>Image courtesy of Dr. Frank Gaillard. Radiopaedia (original file [http://radiopaedia.org/cases/cns-lymphoma-primary here]). Creative Commons BY-SA-NC</ref></sub></gallery> | ||
==Chest, Abdomen, and Pelvic CT== | |||
*Chest, abdomen, and pelvic CT scans may be used to exclude any occult systemic disease from the spread of primary central nervous system lymphoma.<ref name=diagnpstoicsprimarycnslymphoma1>Diagnostics of primary CNS lymphoma. National cancer institute 2016. http://www.cancer.gov/types/lymphoma/hp/primary-cns-lymphoma-treatment-pdq. Accessed on February 19, 2016</ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 16:18, 19 February 2016
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Primary central nervous system lymphoma Microchapters |
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Differentiating Primary Central Nervous System Lymphoma from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Primary central nervous system lymphoma CT On the Web |
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American Roentgen Ray Society Images of Primary central nervous system lymphoma CT |
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Directions to Hospitals Treating Primary central nervous system lymphoma |
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Risk calculators and risk factors for Primary central nervous system lymphoma CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Head CT
- Head CT scan may be helpful in the diagnosis of primary central nervous system lymphoma. Findings on CT scan suggestive of primary central nervous system lymphoma include:[1]
- Supratentorial mass with subependymal extension
- Crossing the corpus callosum
- Lesions are hyperattenuating (70%)
- Enhancement present
- Hemorrhage is distinctly present
- Multiple lesions in patients with HIV/AIDS
- Enhancement on both CT scan and MRI is pronounced and usually homogeneous. Even with larger lesions, there is little mass effect for size and limited surrounding vasogenic edema.
- Low grade tumors differ from the more common high-grade primary central nervous system lymphoma in several ways:[1]
- Deep locations and spinal involvement is more common
- Contrast enhancement is absent, irregular, or only mild
- Disseminated meningeal/intraventricular disease is uncommon, it is observed in 5% of cases at presentation and usually in high grade cases.[1]
- It should be noted that in patients who are immunocompromised (typically HIV/AIDS or post-transplant), enhancement is more heterogeneous.[1]
Gallery
-
![Single image from a non-contrast CT scan demonstrating a vague bilateral hyperdensity crossing the midline.[2]](/images/d/df/Ct_image_primary_central_nervous_system_lymphoma_image_1.jpg)
Single image from a non-contrast CT scan demonstrating a vague bilateral hyperdensity crossing the midline.[2]
![Single image from a non-contrast CT scan demonstrating a vague bilateral hyperdensity crossing the midline.[2]](/index.php/File:Ct_image_primary_central_nervous_system_lymphoma_image_1.jpg)
Chest, Abdomen, and Pelvic CT
- Chest, abdomen, and pelvic CT scans may be used to exclude any occult systemic disease from the spread of primary central nervous system lymphoma.[3]
References
- ↑ 1.0 1.1 1.2 1.3 Radiographic features of primary CNS lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016
- ↑ Image courtesy of Dr. Frank Gaillard. Radiopaedia (original file here). Creative Commons BY-SA-NC
- ↑ Diagnostics of primary CNS lymphoma. National cancer institute 2016. http://www.cancer.gov/types/lymphoma/hp/primary-cns-lymphoma-treatment-pdq. Accessed on February 19, 2016