Primary central nervous system lymphoma pathophysiology: Difference between revisions
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==Gross Pathology== | ==Gross Pathology== | ||
Primary central nervous system lymphoma presents as a solitary or multiple, well-defined or infiltrating mass lesion/s that can arise in the [[cerebral cortex|cortex]], white matter, or deep grey matter (more common in low-grade lesions).<ref name=pathologyofprimarycentralknervouissystemlymphomaradiopeadk1>Pathology of primary central system lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref> | |||
*They may demonstrate areas of [[necrosis]], especially in immunodeficient patients. | |||
*Origin of malignant cells is not well understood as intra-axial CNS does not have lymphatic system.<ref name=pathologyofprimarycentralknervouissystemlymphomaradiopeadk1>Pathology of primary central system lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016</ref> | |||
==Microscopic Pathology== | ==Microscopic Pathology== |
Revision as of 18:37, 18 February 2016
Primary central nervous system lymphoma Microchapters |
Differentiating Primary Central Nervous System Lymphoma from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Pathogenesis
Associated Conditions
Gross Pathology
Primary central nervous system lymphoma presents as a solitary or multiple, well-defined or infiltrating mass lesion/s that can arise in the cortex, white matter, or deep grey matter (more common in low-grade lesions).[1]
- They may demonstrate areas of necrosis, especially in immunodeficient patients.
- Origin of malignant cells is not well understood as intra-axial CNS does not have lymphatic system.[1]
Microscopic Pathology
References
- ↑ 1.0 1.1 Pathology of primary central system lymphoma. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/primary-cns-lymphoma. Accessed on February 18, 2016