Primary central nervous system lymphoma epidemiology and demographics: Difference between revisions
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*Primary central nervous system lymphoma does not have predilections for any age group.<ref name=pcnslwikipediA1>Primary central nervous system lymphoma. Wikipedia 2016. https://en.wikipedia.org/wiki/Primary_central_nervous_system_lymphoma. Accessed on February 18, 2016</ref> | *Primary central nervous system lymphoma does not have predilections for any age group.<ref name=pcnslwikipediA1>Primary central nervous system lymphoma. Wikipedia 2016. https://en.wikipedia.org/wiki/Primary_central_nervous_system_lymphoma. Accessed on February 18, 2016</ref> | ||
*The median age | *The median age of occurrence of primary central nervous system lymphoma in immunocompetent and immunocompromised patients are 53-57 years and 31-35 years, respectively.<ref name="pmid18976024">{{cite journal| author=Bhagavathi S, Wilson JD| title=Primary central nervous system lymphoma. | journal=Arch Pathol Lab Med | year= 2008 | volume= 132 | issue= 11 | pages= 1830-4 | pmid=18976024 | doi=10.1043/1543-2165-132.11.1830 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18976024 }} </ref> | ||
*The peak incidence is between 60 and 70 years old for immunocompetent patients.<ref name="ManentiDi Giuliano2013">{{cite journal|last1=Manenti|first1=G.|last2=Di Giuliano|first2=F.|last3=Bindi|first3=A.|last4=Liberto|first4=V.|last5=Funel|first5=V.|last6=Garaci|first6=F. G.|last7=Floris|first7=R.|last8=Simonetti|first8=G.|title=A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment|journal=Case Reports in Radiology|volume=2013|year=2013|pages=1–5|issn=2090-6862|doi=10.1155/2013/916348}}</ref> | *The peak incidence is between 60 and 70 years old for immunocompetent patients.<ref name="ManentiDi Giuliano2013">{{cite journal|last1=Manenti|first1=G.|last2=Di Giuliano|first2=F.|last3=Bindi|first3=A.|last4=Liberto|first4=V.|last5=Funel|first5=V.|last6=Garaci|first6=F. G.|last7=Floris|first7=R.|last8=Simonetti|first8=G.|title=A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment|journal=Case Reports in Radiology|volume=2013|year=2013|pages=1–5|issn=2090-6862|doi=10.1155/2013/916348}}</ref> | ||
*Young age of the patient should be noted, because it is not typical for primary CNS lymphoma. | *Young age of the patient should be noted, because it is not typical for primary CNS lymphoma. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Epidemiology and Demographics
Prevalence
- Primary central nervous system lymphoma constitutes approximately 3%-4% of all primary brain tumors.[1]
- Primary CNS lymphoma constitues approximately 1%-2% of all lymphomas.[1]
- Primary central nervous system lymphoma has been diagnosed in at least 2% of individuals infected with human immunodeficiency virus, and in 9–14% of acquired immunodeficiency syndrome (AIDS)-autopsies.[2]
- Primary CNS lymphoma is, after toxoplasmosis, the most common cause of focal brain lesions in AIDS patients.[2]
Incidence
- The overall incidence rate of primary central nervous system lymphoma is 0.4 cases per 100,000 individuals per year.[1]
Age
- Primary central nervous system lymphoma does not have predilections for any age group.[3]
- The median age of occurrence of primary central nervous system lymphoma in immunocompetent and immunocompromised patients are 53-57 years and 31-35 years, respectively.[4]
- The peak incidence is between 60 and 70 years old for immunocompetent patients.[1]
- Young age of the patient should be noted, because it is not typical for primary CNS lymphoma.
- Significant increment of incidence rate over time is associated with increased incidence of AIDS and advanced age.
Gender
- Males are more commonly affected with primary central nervous system lymphoma than females. The male to female ratio is approximately 1.5 to 1.[1]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Manenti, G.; Di Giuliano, F.; Bindi, A.; Liberto, V.; Funel, V.; Garaci, F. G.; Floris, R.; Simonetti, G. (2013). "A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment". Case Reports in Radiology. 2013: 1–5. doi:10.1155/2013/916348. ISSN 2090-6862.
- ↑ 2.0 2.1 Haldorsen, Ingfrid S; Kråkenes, Jostein; Goplen, Anne K; Dunlop, Oona; Mella, Olav; Espeland, Ansgar (2008). "AIDS-related primary central nervous system lymphoma: a Norwegian national survey 1989–2003". BMC Cancer. 8 (1): 225. doi:10.1186/1471-2407-8-225. ISSN 1471-2407.
- ↑ Primary central nervous system lymphoma. Wikipedia 2016. https://en.wikipedia.org/wiki/Primary_central_nervous_system_lymphoma. Accessed on February 18, 2016
- ↑ Bhagavathi S, Wilson JD (2008). "Primary central nervous system lymphoma". Arch Pathol Lab Med. 132 (11): 1830–4. doi:10.1043/1543-2165-132.11.1830. PMID 18976024.