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Latest revision as of 18:00, 18 September 2017

Lymphogranuloma venereum Microchapters

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Patient Information

Overview

Historical Perspective

Pathophysiology

Causes

Classification

Differentiating Lymphogranuloma venereum from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Prevention

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nate Michalak, B.A.

Overview

Primary LGV is characterized by a small, nontender papule or ulcer. The primary lesion is typically unnoticed so few patients present at this stage. Majority of patients that do present are male. Secondary LGV is characterized by tender, swollen lymph nodes, typically unilateral, known as buboes. Enlarged inguinal and/or femoral lymph nodes occur after primary lesion of anterior genital area. Enlarged iliac and/or perirectal lymph nodes occure after primary lesion of posterior genital area. 20% of patients present with "groove sign". Buboes may be indurated or draining sinuses. Tertiary LGV is characterized by [perirectal]] fistulas and/or strictures, ulcerative proctitis, and/or Elephantiasis of gentials. Males may present with "saxophone penis". Females may present with with ulceration and thickening of the vulva.

Physcial Examination

Vital Signs

  • Fever during later stages

Primary LGV

  • Patients presenting at first stage of LGV usually have a small, nontender papule or ulcer.[1]
  • Common locations in males:
  • Common locations in females:
  • Due to lesion location on each sex, more males present at this stage than females.[1]

Secondary LGV

  • Patients present with tender, swollen lymph nodes, typically unilateral, known as buboes.
  • Enlarged inguinal and/or femoral lymph nodes occur after primary lesion of anterior genital area (anterior vulva, penis, or urethra).
  • Enlarged iliac and/or perirectal lymph nodes occure after primary lesion of posterior genital area (posterior vulva, vagina, or anus).
  • Inguinal inflammation more common in men while anorectal lymphadenopathy more common in women
  • 20% of patients develop "groove sign": enlarged inguinal and femoral lymph nodes separated by the inguinal ligament.[2]
  • Buboes may present as indurated abscesses or ruptured, draining sinuses.[3]

Tertiary LGV

Gallery

References

  1. 1.0 1.1 Ceovic R, Gulin SJ (2015). "Lymphogranuloma venereum: diagnostic and treatment challenges". Infect Drug Resist. 8: 39–47. doi:10.2147/IDR.S57540. PMC 4381887. PMID 25870512.
  2. Roest RW, van der Meijden WI, European Branch of the International Union against Sexually Transmitted Infection and the European Office of the World Health Organization (2001). "European guideline for the management of tropical genito-ulcerative diseases". Int J STD AIDS. 12 Suppl 3: 78–83. PMID 11589803.
  3. Mabey, D (2002). "Lymphogranuloma venereum". Sexually Transmitted Infections. 78 (2): 90–92. doi:10.1136/sti.78.2.90. ISSN 1368-4973.
  4. Lynch CM, Felder TL, Schwandt RA, Shashy RG (1999). "Lymphogranuloma venereum presenting as a rectovaginal fistula". Infect Dis Obstet Gynecol. 7 (4): 199–201. doi:10.1155/S1064744999000344. PMC 1784745. PMID 10449269.
  5. Koley S, Mandal RK (2013). "Saxophone penis after unilateral inguinal bubo of lymphogranuloma venereum". Indian J Sex Transm Dis. 34 (2): 149–51. doi:10.4103/0253-7184.120575. PMC 3841672. PMID 24339471.

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