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==Differentiating Seminoma from other Diseases==
==Differentiating Seminoma from other Diseases==
The most common presentation of testicular seminoma is a painless testicular mass.<ref name=clinicslpresntatioontesticularseminoma1>Clinical presentation of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016</ref> The main differential for testicular mass in young adults is non-seminomatous germ cell tumor (NGCT) which usually appear more heterogenous, often with [[cyst]]s and [[calcification]].<ref name=differentialdiagnopsisoftesticulartyeratoma1>Differential diagnosis of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016</ref> Lymphadenopathy of non-seminomatous germ cell tumor may enhance more heterogenously. Testicular lymphoma is the main differential diagnosis to consider when [[para-aortic lymphadenopathy]] is the presenting finding or in the setting of bilateral testicular lesions.<ref name=differentialdiagnopsisoftesticulartyeratoma1>Differential diagnosis of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016</ref>
The most common presentation of testicular seminoma is a painless testicular mass.<ref name=clinicslpresntatioontesticularseminoma1>Clinical presentation of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016</ref> The main differential for testicular mass in young adults is non-seminomatous germ cell tumor (NGCT) which usually appear more heterogenous, often with [[cyst]]s and [[calcification]].<ref name=differentialdiagnopsisoftesticulartyeratoma1>Differential diagnosis of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016</ref> Lymphadenopathy of non-seminomatous germ cell tumor may enhance more heterogenously. Testicular lymphoma is the main differential diagnosis to consider when [[para-aortic lymphadenopathy]] is the presenting finding or in the setting of bilateral testicular lesions.<ref name=differentialdiagnopsisoftesticulartyeratoma1>Differential diagnosis of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016</ref>
Testicular seminoma must be differentiated from:<ref name=Unilateraltesticularlesions1>Unilateral testicular lesions. Dr Yuranga Weerakkody and Dr Vinod G Maller et al. Radiopaedia 2016. http://radiopaedia.org/articles/unilateral-testicular-lesions. Accessed on February 25, 2016</ref><ref name=Bilateraltesticularlesions1>Bilateral testicular lesions. Dr Matt A. Morgan and Dr Vinod G Maller et al. Radiopaedia 2016. http://radiopaedia.org/articles/bilateral-testicular-lesions. Accessed on February 25, 2016</ref>
{{familytree/start |summary=Testicular mass}}
{{familytree |boxstyle=background: #DCDCDC;| | | | | | | | | | | | | A01| | | | | | | | | | | | | |A01=<div style="width: 12em; padding:0.2em;">'''Differential diagnosis of testicular seminoma'''</div>}}
{{familytree |boxstyle=background: #DCDCDC;| | | | | | | |,|-|-|-|-|-|^|-|-|-|-|-|.| | | | | | | | | | | | | | |}}
{{familytree |boxstyle=background: #DCDCDC;| | | | | | | B01 | | | | | | | | | | B02 | | | | | | | | | | | | | | | |B01=<div style="width: 12em; padding:0em;">'''Unilateral testicular mass''' </div>|B02=<div style="width: 12em; padding:0em;">'''Bilateral testicular mass'''</div>}}
{{familytree |boxstyle=background: #DCDCDC;| | | | | | | F01 | | | | | | | | | | F02 | | | | | | | | | | | | | | | |F01=<div style="width: 12em; padding:0em;">'''WHO grade I / II''' </div>|F02=<div style="width: 12em; padding:0em;">'''WHO grade II'''</div>}}
{{familytree |boxstyle=background: #DCDCDC;| | | | | | | |!| | | | | |,|-|-|-|v|-|^|-|v|-|-|-|.| | | | | | | | | | | | | | |}}
{{familytree |boxstyle=background: #DCDCDC;| | | | | | | |!| | | | | C01 | | C02 | | C03 | | C04 | | | | | | | | | | | | | |C01=<div style="width: 9em; padding:0.2em;">'''[[Fibrillary astrocytoma]]''' </div>|C02=<div style="width: 9em; padding:0.2em;">'''[[Gemistocytic astrocytoma]]'''</div>|C03=<div style="width: 9em; padding:0.2em;">'''[[Protoplasmic astrocytoma]]'''</div>|C04=<div style="width: 9em; padding:0.2em;">'''[[Oligoastrocytoma]]'''</div>}}
{{familytree |boxstyle=background: #DCDCDC;| |,|-|-|-|v|-|^|-|v|-|-|-|.| | | | | | | | | | | | | | | | | |}}
{{familytree |boxstyle=background: #DCDCDC;| D01 | | D02 | | D03 | | D04 | | | | | | | | | | | | | | | | | | | | |D01=<div style="width: 9em; padding:0.2em;">'''[[Pilocytic astrocytoma]]''' </div>|D02=<div style="width: 9em; padding:0.2em;">'''Pilomyxoid astrocytoma'''</div>|D03=<div style="width: 9em; padding:0.2em;">'''[[Subependymal giant cell astrocytoma]]'''</div>|D04=<div style="width: 9em; padding:0.2em;">'''[[Pleomorphic xanthoastrocytoma]]'''</div>}}
{{familytree |boxstyle=background: #DCDCDC;| E01 | | E02 | | E03 | | E04 | | | | | | | | | | | | | | | | | | | | |E01=<div style="width: 9em; padding:0.2em;">'''WHO grade I''' </div>|E02=<div style="width: 9em; padding:0.2em;">'''WHO grade II'''</div>|E03=<div style="width: 9em; padding:0.2em;">'''WHO grade I'''</div>|E04=<div style="width: 9em; padding:0.2em;">'''WHO grade II'''</div>}}
{{familytree/end}}


==References==
==References==

Revision as of 15:49, 25 February 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Differentiating Seminoma from other Diseases

The most common presentation of testicular seminoma is a painless testicular mass.[1] The main differential for testicular mass in young adults is non-seminomatous germ cell tumor (NGCT) which usually appear more heterogenous, often with cysts and calcification.[2] Lymphadenopathy of non-seminomatous germ cell tumor may enhance more heterogenously. Testicular lymphoma is the main differential diagnosis to consider when para-aortic lymphadenopathy is the presenting finding or in the setting of bilateral testicular lesions.[2]

Testicular seminoma must be differentiated from:[3][4]


 
 
 
 
 
 
 
 
 
 
 
 
Differential diagnosis of testicular seminoma
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Unilateral testicular mass
 
 
 
 
 
 
 
 
 
Bilateral testicular mass
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
WHO grade I / II
 
 
 
 
 
 
 
 
 
WHO grade II
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Pilomyxoid astrocytoma
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
WHO grade I
 
WHO grade II
 
WHO grade I
 
WHO grade II
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

References

  1. ↑ Clinical presentation of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016
  2. ↑ 2.0 2.1 Differential diagnosis of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016
  3. ↑ Unilateral testicular lesions. Dr Yuranga Weerakkody and Dr Vinod G Maller et al. Radiopaedia 2016. http://radiopaedia.org/articles/unilateral-testicular-lesions. Accessed on February 25, 2016
  4. ↑ Bilateral testicular lesions. Dr Matt A. Morgan and Dr Vinod G Maller et al. Radiopaedia 2016. http://radiopaedia.org/articles/bilateral-testicular-lesions. Accessed on February 25, 2016

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