Donovanosis physical examination: Difference between revisions
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Clinically, the disease is commonly characterized as painless, progressive ulcerative lesions without regional [[lymphadenopathy]]. The lesions are highly vascular (i.e., beefy red appearance) and bleed easily on contact. However, the clinical presentation also can include hypertrophic, necrotic, or sclerotic variants. | Clinically, the disease is commonly characterized as painless, progressive ulcerative lesions without regional [[lymphadenopathy]]. The lesions are highly vascular (i.e., beefy red appearance) and bleed easily on contact. However, the clinical presentation also can include hypertrophic, necrotic, or sclerotic variants. | ||
=== | Typical lesion characteristics include: | ||
*Beefy red color | |||
*Nontender | |||
*Emit rank odor | |||
*Elevated above skin | |||
*Smooth, rolled edge | |||
*Serpiginous outline<ref name="Richens">{{cite journal| author=Richens J| title=The diagnosis and treatment of donovanosis (granuloma inguinale). | journal=Genitourin Med | year= 1991 | volume= 67 | issue= 6 | pages= 441-52 | pmid=1774048 | doi= | pmc=PMC1194766 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1774048 }} </ref> | |||
Four variants can be further classified according to their clinical presentation:<ref name=" O'Farrell">{{cite journal| author=O'Farrell N| title=Donovanosis. | journal=Sex Transm Infect | year= 2002 | volume= 78 | issue= 6 | pages= 452-7 | pmid=12473810 | doi= | pmc=PMC1758360 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12473810 }} </ref> | |||
{| style="font-size: 85%;" | |||
! style="width: 160px; background: #4479BA; text-align: center;" |{{fontcolor|#FFF|Type}} | |||
! style="width: 300px; background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Clinical Appearance}} | |||
|- | |||
| style="background: #DCDCDC; padding: 5px; text-align: center;" | '''Ulcerogrnulomatous''' | |||
| style="background: #F5F5F5; padding: 5px;" | beefy red, non-tender, bleeds easily | |||
|- | |||
| style="background: #DCDCDC; padding: 5px; text-align: center;" | '''Hypertrophic or Verrucous''' | |||
| style="background: #F5F5F5; padding: 5px;" | irregular edge, dry | |||
|- | |||
| style="background: #DCDCDC; padding: 5px; text-align: center;" | '''Necrotic''' | |||
| style="background: #F5F5F5; padding: 5px;" | foul smelling, deep, tissue destruction | |||
|- | |||
| style="background: #DCDCDC; padding: 5px; text-align: center;" | '''Sclerotic''' | |||
| style="background: #F5F5F5; padding: 5px;" | dry, cicatricial, fibrous scar tissue | |||
|} | |||
===Common Locations in Males=== | ===Common Locations in Males=== | ||
Revision as of 19:48, 2 March 2016
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Donovanosis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Donovanosis physical examination On the Web |
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American Roentgen Ray Society Images of Donovanosis physical examination |
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Risk calculators and risk factors for Donovanosis physical examination |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]; Kiran Singh, M.D. [3]; Nate Michalak, B.A.
Overview
Clinically, the disease is commonly characterized as painless, progressive ulcerative lesions without regional lymphadenopathy.
Physical Examination
Clinically, the disease is commonly characterized as painless, progressive ulcerative lesions without regional lymphadenopathy. The lesions are highly vascular (i.e., beefy red appearance) and bleed easily on contact. However, the clinical presentation also can include hypertrophic, necrotic, or sclerotic variants.
Typical lesion characteristics include:
- Beefy red color
- Nontender
- Emit rank odor
- Elevated above skin
- Smooth, rolled edge
- Serpiginous outline[1]
Four variants can be further classified according to their clinical presentation:[2]
| Type | Clinical Appearance |
|---|---|
| Ulcerogrnulomatous | beefy red, non-tender, bleeds easily |
| Hypertrophic or Verrucous | irregular edge, dry |
| Necrotic | foul smelling, deep, tissue destruction |
| Sclerotic | dry, cicatricial, fibrous scar tissue |
Common Locations in Males
Common Locations in Females
Extragenital Lesion Locations
Gallery
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![Genital ulcer in a male patient with Donovanosis.Adapted from Dermatology Atlas.[3]](/images/5/5d/SOA-Donovanosis-male.jpg)
Genital ulcer in a male patient with Donovanosis.Adapted from Dermatology Atlas.[3]
-
![Genital ulcer in a female patient with Donovanosis.Adapted from Dermatology Atlas.[3]](/images/e/e7/SOA-Donovanosis-female.jpg)
Genital ulcer in a female patient with Donovanosis.Adapted from Dermatology Atlas.[3]
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![Donovanosis. Adapted from Dermatology Atlas.[3]](/images/3/38/Donovanosis01.jpg)
Donovanosis. Adapted from Dermatology Atlas.[3]
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![Granuloma inguinale, or Donovanosis, accompanied by perianal skin ulceration due to the bacterium, Klebsiella granulomatis. Adapted from Dermatology Atlas.[3]](/images/0/0b/Enterobacteria62.jpeg)
Granuloma inguinale, or Donovanosis, accompanied by perianal skin ulceration due to the bacterium, Klebsiella granulomatis. Adapted from Dermatology Atlas.[3]
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![Donovanosis of penis. Adapted from Dermatology Atlas.[3]](/images/1/17/Enterobacteria54.jpeg)
Donovanosis of penis. Adapted from Dermatology Atlas.[3]
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![Donovanosis of penis. Adapted from Dermatology Atlas.[3]](/images/a/a6/Enterobacteria53.jpeg)
Donovanosis of penis. Adapted from Dermatology Atlas.[3]
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![Preputial granulomatous lesion due to Donovanosis. Adapted from Dermatology Atlas.[3]](/images/7/7f/Enterobacteria51.jpeg)
Preputial granulomatous lesion due to Donovanosis. Adapted from Dermatology Atlas.[3]
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![Bilaterally infected inguinal lymph nodes due to a Calymmatobacterium granulomatis bacteria. Adapted from Dermatology Atlas.[3]](/images/a/a2/Enterobacteria49.jpeg)
Bilaterally infected inguinal lymph nodes due to a Calymmatobacterium granulomatis bacteria. Adapted from Dermatology Atlas.[3]
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![This patient presented with a case of systemically disseminated Donovanosis of the ankle due to C. granulomatis bacteria. From Public Health Image Library (PHIL). [4]](/images/4/4a/Granuloma_inguinale11.jpeg)
This patient presented with a case of systemically disseminated Donovanosis of the ankle due to C. granulomatis bacteria. From Public Health Image Library (PHIL). [4]
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![This male presented with a penile lesion that was found to be granuloma inguinale, also called “genital ulcerative disease”. From Public Health Image Library (PHIL). [4]](/images/3/3c/Granuloma_inguinale10.jpeg)
This male presented with a penile lesion that was found to be granuloma inguinale, also called “genital ulcerative disease”. From Public Health Image Library (PHIL). [4]
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![This male presented with a penile lesion of roughly 40 days duration that was determined to be granuloma inguinale. From Public Health Image Library (PHIL). [4]](/images/f/f8/Granuloma_inguinale09.jpeg)
This male presented with a penile lesion of roughly 40 days duration that was determined to be granuloma inguinale. From Public Health Image Library (PHIL). [4]
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![This 19 year old woman presented with an perianal granuloma inguinale lesion of about 8 months duration. From Public Health Image Library (PHIL). [4]](/images/5/50/Granuloma_inguinale08.jpeg)
This 19 year old woman presented with an perianal granuloma inguinale lesion of about 8 months duration. From Public Health Image Library (PHIL). [4]
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![This patient presented with an ulcerated glans penis due to Donovanosis, or granuloma inguinale. From Public Health Image Library (PHIL). [4]](/images/a/a4/Granuloma_inguinale07.jpeg)
This patient presented with an ulcerated glans penis due to Donovanosis, or granuloma inguinale. From Public Health Image Library (PHIL). [4]
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![This image depicts an intravaginal view revealing a cervical lesion, which had been diagnosed as a case of Donovanosis, also known as granuloma inguinale. From Public Health Image Library (PHIL). [4]](/images/2/2e/Granuloma_inguinale06.jpeg)
This image depicts an intravaginal view revealing a cervical lesion, which had been diagnosed as a case of Donovanosis, also known as granuloma inguinale. From Public Health Image Library (PHIL). [4]
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![This image depicts the penis of a male with its foreskin retracted, revealing a suppurative lesion involving the glans and prepuce. From Public Health Image Library (PHIL). [4]](/images/1/10/Granuloma_inguinale05.jpeg)
This image depicts the penis of a male with its foreskin retracted, revealing a suppurative lesion involving the glans and prepuce. From Public Health Image Library (PHIL). [4]
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![This image depicts the penis of a male patient who had presented with a lesion located on the lateral preputial skin just proximal to the corona of the glans. The lesion was characterized as a penile granulomata, due to a case of Donovanosis, or granuloma inguinale. From Public Health Image Library (PHIL). [4]](/images/2/2a/Granuloma_inguinale03.jpeg)
This image depicts the penis of a male patient who had presented with a lesion located on the lateral preputial skin just proximal to the corona of the glans. The lesion was characterized as a penile granulomata, due to a case of Donovanosis, or granuloma inguinale. From Public Health Image Library (PHIL). [4]
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![This patient showed manifestations of granuloma inguinale, also known as Donovanosis, involving swelling and subcutaneous granulomas of the inguinal lymph nodes, bilaterally. From Public Health Image Library (PHIL). [4]](/images/8/82/Granuloma_inguinale02.jpeg)
This patient showed manifestations of granuloma inguinale, also known as Donovanosis, involving swelling and subcutaneous granulomas of the inguinal lymph nodes, bilaterally. From Public Health Image Library (PHIL). [4]
-
![This was a very large erosive cutaneous lesion in the perineal region of this patient, which had been diagnosed as Donovanosis, otherwise known as granuloma inguinale. From Public Health Image Library (PHIL). [4]](/images/6/6d/Granuloma_inguinale01.jpeg)
This was a very large erosive cutaneous lesion in the perineal region of this patient, which had been diagnosed as Donovanosis, otherwise known as granuloma inguinale. From Public Health Image Library (PHIL). [4]
![Genital ulcer in a male patient with Donovanosis.Adapted from Dermatology Atlas.[3]](/index.php/File:SOA-Donovanosis-male.jpg)
![Genital ulcer in a female patient with Donovanosis.Adapted from Dermatology Atlas.[3]](/index.php/File:SOA-Donovanosis-female.jpg)
![Donovanosis. Adapted from Dermatology Atlas.[3]](/index.php/File:Donovanosis01.jpg)
![Granuloma inguinale, or Donovanosis, accompanied by perianal skin ulceration due to the bacterium, Klebsiella granulomatis. Adapted from Dermatology Atlas.[3]](/index.php/File:Enterobacteria62.jpeg)
![Donovanosis of penis. Adapted from Dermatology Atlas.[3]](/index.php/File:Enterobacteria54.jpeg)
![Donovanosis of penis. Adapted from Dermatology Atlas.[3]](/index.php/File:Enterobacteria53.jpeg)
![Preputial granulomatous lesion due to Donovanosis. Adapted from Dermatology Atlas.[3]](/index.php/File:Enterobacteria51.jpeg)
![Bilaterally infected inguinal lymph nodes due to a Calymmatobacterium granulomatis bacteria. Adapted from Dermatology Atlas.[3]](/index.php/File:Enterobacteria49.jpeg)
![This patient presented with a case of systemically disseminated Donovanosis of the ankle due to C. granulomatis bacteria. From Public Health Image Library (PHIL). [4]](/index.php/File:Granuloma_inguinale11.jpeg)
![This male presented with a penile lesion that was found to be granuloma inguinale, also called “genital ulcerative disease”. From Public Health Image Library (PHIL). [4]](/index.php/File:Granuloma_inguinale10.jpeg)
![This male presented with a penile lesion of roughly 40 days duration that was determined to be granuloma inguinale. From Public Health Image Library (PHIL). [4]](/index.php/File:Granuloma_inguinale09.jpeg)
![This 19 year old woman presented with an perianal granuloma inguinale lesion of about 8 months duration. From Public Health Image Library (PHIL). [4]](/index.php/File:Granuloma_inguinale08.jpeg)
![This patient presented with an ulcerated glans penis due to Donovanosis, or granuloma inguinale. From Public Health Image Library (PHIL). [4]](/index.php/File:Granuloma_inguinale07.jpeg)
![This image depicts an intravaginal view revealing a cervical lesion, which had been diagnosed as a case of Donovanosis, also known as granuloma inguinale. From Public Health Image Library (PHIL). [4]](/index.php/File:Granuloma_inguinale06.jpeg)
![This image depicts the penis of a male with its foreskin retracted, revealing a suppurative lesion involving the glans and prepuce. From Public Health Image Library (PHIL). [4]](/index.php/File:Granuloma_inguinale05.jpeg)
![This image depicts the penis of a male patient who had presented with a lesion located on the lateral preputial skin just proximal to the corona of the glans. The lesion was characterized as a penile granulomata, due to a case of Donovanosis, or granuloma inguinale. From Public Health Image Library (PHIL). [4]](/index.php/File:Granuloma_inguinale03.jpeg)
![This patient showed manifestations of granuloma inguinale, also known as Donovanosis, involving swelling and subcutaneous granulomas of the inguinal lymph nodes, bilaterally. From Public Health Image Library (PHIL). [4]](/index.php/File:Granuloma_inguinale02.jpeg)
![This was a very large erosive cutaneous lesion in the perineal region of this patient, which had been diagnosed as Donovanosis, otherwise known as granuloma inguinale. From Public Health Image Library (PHIL). [4]](/index.php/File:Granuloma_inguinale01.jpeg)
References
- ↑ Richens J (1991). "The diagnosis and treatment of donovanosis (granuloma inguinale)". Genitourin Med. 67 (6): 441–52. PMC 1194766. PMID 1774048.
- ↑ O'Farrell N (2002). "Donovanosis". Sex Transm Infect. 78 (6): 452–7. PMC 1758360. PMID 12473810.
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 "Dermatology Atlas".
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9 "Public Health Image Library (PHIL)".