Intravascular large B-cell lymphoma: Difference between revisions

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==Differentiating type page name here from other Diseases==
==Differentiating type page name here from other Diseases==
Intravascular large B-cell lymphoma must be differentiated from other diseases such as:
Intravascular large B-cell lymphoma must be differentiated from other diseases such as:
 
* [[Hepatosplenic T-cell lymphoma]]
 
* [[B-cell chronic lymphocytic leukemia]]
* [[Mantle cell lymphoma]]
* [[Splenic marginal zone lymphoma]]
== Epidemiology and Demographics ==
== Epidemiology and Demographics ==
===Age===
===Age===
The incidence of intravascular large B-cell lymphoma increases with age; the median age at diagnosis is 67 years.
The incidence of intravascular large B-cell lymphoma increases with age; the median age at diagnosis is 67 years.<ref name=seer.cancer.gov>Intravascular large B-cell lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf5ae3e27c3994bd54a7/. Accessed on March 09, 2016 </ref>
===Gender===
===Gender===
Intravascular large B-cell lymphoma affects men and women equally.
Intravascular large B-cell lymphoma affects men and women equally.<ref name=seer.cancer.gov>Intravascular large B-cell lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf5ae3e27c3994bd54a7/. Accessed on March 09, 2016 </ref>


== Risk Factors ==
== Risk Factors ==

Revision as of 17:18, 9 March 2016

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Synonyms and keywords:

Overview

Classification

Intravascular large B-cell lymphoma may be classified into either

Intravascular large B-cell lymphoma classification
Name Description

Pathophysiology

Microscopic Pathology

Causes

There are no established causes for intravascular large B-cell lymphoma.

Differentiating type page name here from other Diseases

Intravascular large B-cell lymphoma must be differentiated from other diseases such as:

Epidemiology and Demographics

Age

The incidence of intravascular large B-cell lymphoma increases with age; the median age at diagnosis is 67 years.[1]

Gender

Intravascular large B-cell lymphoma affects men and women equally.[1]

Risk Factors

There are no established risk factors for intravascular large B-cell lymphoma.

Screening

According to the the U.S. Preventive Service Task Force (USPSTF), there is insufficient evidence to recommend routine screening for intravascular large B-cell lymphoma.[2]

Natural History, Complications and Prognosis

  • People with this type of lymphoma can also develop a very serious condition where certain parts of the immune system are activated (hemophagocytic syndrome).[1]
  • Hemophagocytic syndrome causes:


Diagnosis

Symptoms

Symptoms of the intravascular large B-cell lymphoma include:[1]

Physical Examination

Vitals

Skin

  • Skin rash

HEENT

Thorax

Abdomen

Extremities

Laboratory Findings

Laboratory tests for intravascular large B-cell lymphoma include:[1]

Biopsy

Lymph node biopsy is diagnostic of intravascular large B-cell lymphoma.

Other Imaging Findings

CT, MRI, and PET scan may be helpful in the diagnosis of intravascular large B-cell lymphoma.

Treatment

Medical Therapy

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Intravascular large B-cell lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf5ae3e27c3994bd54a7/. Accessed on March 09, 2016
  2. ↑ Recommendations. U.S Preventive Services Task Force. Accessed on March 9, 2016

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