Cardiac amyloidosis differential diagnosis: Difference between revisions
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==Overview== | ==Overview== | ||
[[Cardiomyopathy]] with [[congestive heart failure]] is the most common amyloidosis | [[Cardiomyopathy]] with [[congestive heart failure]] is the most common presentation of cardiac amyloidosis. Other common causes of a [[cardiomyopathy]] should be excluded, and cardiac amyloidosis should be considered in the absence of a history of myocaridal [[ischemia]], [[myocardial infarction]] or presence of [[coronary artery disease]] risk factors.<ref name="pmid10319082">{{cite journal |author=Gertz MA, Lacy MQ, Dispenzieri A |title=Amyloidosis: recognition, confirmation, prognosis, and therapy |journal=[[Mayo Clinic Proceedings. Mayo Clinic]] |volume=74 |issue=5 |pages=490–4 |year=1999 |month=May |pmid=10319082 |doi=10.4065/74.5.490 |url=http://linkinghub.elsevier.com/retrieve/pii/S0025-6196(11)65130-6 |accessdate=2012-02-13}}</ref> Cardiac amyloidosis should be included in the differential diagnoses in patients with [[congestive heart failure|unexplained congestive heart failure]] who have no history of [[Valvular heart disease]], [[hypertension|long-standing hypertension]] or myocardial [[ischemia]].<ref name="pmid10319082">{{cite journal |author=Gertz MA, Lacy MQ, Dispenzieri A |title=Amyloidosis: recognition, confirmation, prognosis, and therapy |journal=[[Mayo Clinic Proceedings. Mayo Clinic]] |volume=74 |issue=5 |pages=490–4 |year=1999 |month=May |pmid=10319082 |doi=10.4065/74.5.490 |url=http://linkinghub.elsevier.com/retrieve/pii/S0025-6196(11)65130-6 |accessdate=2012-02-13}}</ref> | ||
==Differentiating Cardiac Amyloidosis from Other Diseases== | ==Differentiating Cardiac Amyloidosis from Other Diseases== |
Revision as of 18:34, 29 October 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]; Aarti Narayan, M.B.B.S [3]; Lakshmi Gopalakrishnan, M.B.B.S. [4]
Overview
Cardiomyopathy with congestive heart failure is the most common presentation of cardiac amyloidosis. Other common causes of a cardiomyopathy should be excluded, and cardiac amyloidosis should be considered in the absence of a history of myocaridal ischemia, myocardial infarction or presence of coronary artery disease risk factors.[1] Cardiac amyloidosis should be included in the differential diagnoses in patients with unexplained congestive heart failure who have no history of Valvular heart disease, long-standing hypertension or myocardial ischemia.[1]
Differentiating Cardiac Amyloidosis from Other Diseases
Cardiac amyloidosis should be differentiated from the following:
- Hypertension
- Anderson-Fabry disease
- Hypertrophic cardiomyopathy
- Cardiac sarcoidosis
- Cardiac lymphoma
Cardiac amyloidosis is differentiated from the above disorders by the presence of the following:
- Presence of low voltage EKG
- Echo features such as:
- Diffuse increased echogenicity
- Valve thickening
- Thickened interatrial septum
- Global late gadolinium enhancement (LGE) on MRI
References
- ↑ 1.0 1.1 Gertz MA, Lacy MQ, Dispenzieri A (1999). "Amyloidosis: recognition, confirmation, prognosis, and therapy". Mayo Clinic Proceedings. Mayo Clinic. 74 (5): 490–4. doi:10.4065/74.5.490. PMID 10319082. Retrieved 2012-02-13. Unknown parameter
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