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*Prior to the introduction of penicillin in 1940 as an antibiotic, osteomyelitis was usually treated with crude surgical excision of necrotic tissue or limb amputation. | *Prior to the introduction of penicillin in 1940 as an antibiotic, osteomyelitis was usually treated with crude surgical excision of necrotic tissue or limb amputation. | ||
*Penicillin significantly reduced mortality until 1950, after the emergence of penicillin-resistant bacteria, most commonly '''Staphylococcus'''. | *Penicillin significantly reduced mortality until 1950, after the emergence of penicillin-resistant bacteria, most commonly '''Staphylococcus'''. | ||
*In 1970, NJ Blockey, JT Watson, and TA McAllister reevaluated the treatment of osteomyelitis with antibiotics and surgery, which reflects current clinical practices. | *In 1970, NJ Blockey, JT Watson, and TA McAllister reevaluated the treatment of osteomyelitis with antibiotics and surgery, which reflects current clinical practices.<ref name="Klenerman2007">{{cite journal|last1=Klenerman|first1=L.|title=A history of osteomyelitis from the Journal of Bone and Joint Surgery: 1948 TO 2006|journal=Journal of Bone and Joint Surgery - British Volume|volume=89-B|issue=5|year=2007|pages=667–670|issn=0301-620X|doi=10.1302/0301-620X.89B5.19170}}</ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | |||
[[Category:Orthopedics]] | [[Category:Orthopedics]] | ||
[[Category:Bacterial diseases]] | [[Category:Bacterial diseases]] | ||
Revision as of 20:44, 22 March 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nate Michalak, B.A.
Overview
Historical Perspective
- Osteomyelitis has been identified in the fractured spine of a dimetrodon Permian reptile, which existed 291 to 250 million years ago.
- Osteomyelitis may have been been first described by Hippocrates (460-370 BC).
- Before Auguste Nelation termed the disease "osteomyelitis" in 1844, the disease was referred to as "abscessus in medulla", "necrosis" and "boil of the bone marrow".
- Prior to the introduction of penicillin in 1940 as an antibiotic, osteomyelitis was usually treated with crude surgical excision of necrotic tissue or limb amputation.
- Penicillin significantly reduced mortality until 1950, after the emergence of penicillin-resistant bacteria, most commonly Staphylococcus.
- In 1970, NJ Blockey, JT Watson, and TA McAllister reevaluated the treatment of osteomyelitis with antibiotics and surgery, which reflects current clinical practices.[1]
References
- ↑ Klenerman, L. (2007). "A history of osteomyelitis from the Journal of Bone and Joint Surgery: 1948 TO 2006". Journal of Bone and Joint Surgery - British Volume. 89-B (5): 667–670. doi:10.1302/0301-620X.89B5.19170. ISSN 0301-620X.