Ovarian cancer pathophysiology: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
| Line 6: | Line 6: | ||
==Pathophysiology== | ==Pathophysiology== | ||
==Gross Patholgy== | ==Gross Patholgy== | ||
Revision as of 17:56, 12 April 2016
|
Ovarian cancer Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Ovarian cancer pathophysiology On the Web |
|
American Roentgen Ray Society Images of Ovarian cancer pathophysiology |
|
Risk calculators and risk factors for Ovarian cancer pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Ovarian cancer is often diagnosed late resulting in a poor overall outcome for the patient. Pathological findings, therefore, often only occur in advanced symptomatic onset and tend to present more as severe pathologic outcomes.
Pathophysiology
Gross Patholgy
| Ovarian Carcinomas Subtype | Features on Gross Pathology |
| ovarian serous cystadenocarcinoma |
Typically solid with multiple cystic areas. Often >10 cm. |
| ovarian mucinous cystadenocarcinoma |
|
| Endometrioid carcinoma of the ovary |
|
Microscopic Pathology
Histologic subtypes of epithelial ovarian tumor
include:[1][2][3][4]
- Surface epithelial stromal ovarian tumor (60-70%)
- ovarian serous tumor
- ovarian serous cystadenoma: ~60% of serous tumor
- ovarian borderline serous cystadenoma: ~15% of serous tumor
- ovarian serous cystadenocarcinoma: ~25% of serous tumor; commonest malignant ovarian tumour
- ovarian mucinous tumor: ~20% of all ovarian tumor
- ovarian mucinous cystadenoma: ~80% of mucinous tumor
- ovarian bordeline mucinous cystadenoma: 10-15% of mucinous tumor
- ovarian mucinous cystadenocarcinoma: 5-10% of mucinous tumor
- ovarian endometrioid tumour: 8-15% of all ovarian tumor
- clear cell ovarian carcinoma: ~5% of ovarian cancer
- Brenner tumour: ~2.5% of ovarian epithelial neoplasms
- squamous cell carcinoma of the ovary
- ovarian cystadenofibroma / ovarian adenofibroma: can be serous, mucinous, endometrioid, clear cell or mixed
- ovarian cystadenocarcinofibroma: extremely rare
- undifferentiated carcinoma of the ovary: ~4% of all ovarian tumor
| Vulvar Carcinomas Subtype | Features on Histopathological Microscopic Analysis | Image |
| Ovarian serous cystadenocarcinoma |
|
 |
| ovarian mucinous cystadenocarcinoma |
|
 |
| Endometrioid carcinoma of the ovary |
|
Clear cell tumor
Clear cell tumors can be either clear cell adenocarcinomas or clear cell sarcomas.On microscopic pathological examination, they are composed of cells with clear cytoplasm (that contains glycogen) and hob nail cells (from which the glycogen has been secreted).The pattern may be glandular, papillary or solid.
Shown below is an image of Overian clear cell adenocarcinoma.(H&E stain,very high mag)
Video
Shown below is a video of clear cell adenocarcinoma of the vagina.
{{#ev:youtube|qO2w8VLf690}}
References
- ↑ Hoffman, Barbara (2012). Williams gynecology. New York: McGraw-Hill Medical. ISBN 9780071716727.
- ↑ Malignant melanoma. Libre pathology. http://librepathology.org/wiki/index.php/Malignant_melanoma. URL Accessed on September 30, 2015
- ↑ Basal cell carcinoma . Libre pathology. http://librepathology.org/wiki/index.php/Basal_cell_carcinoma. URL Accessed on September 30, 2015
- ↑ Squamous cell carcinoma. Libre pathology. http://librepathology.org/wiki/index.php/Squamous_cell_carcinoma. URL Accessed on September 30, 2015