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==Overview==
==Overview==
Otitis externa must be differentiated from other diseases that cause [[earache]] and drainage from the ear ([[otorrhea]]), such as [[otitis media]].
Acute otitis externa must be differentiated from other diseases that cause [[otalgia]], ear [[itching]], [[otorrhea]], [[erythema]] and [[edema]] of the [[ear canal]], [[hearing loss]], ear pressure, and [[dermatitis]]. Malignant otitis externa must be differentiated from other diseases that cause [[facial palsy]], [[osteitis]], [[difficulty swallowing]], and [[hoarseness]].


==Differentiating Otitis Externa From Other Diseases==
Acute otitis externa must be differentiated from other diseases that cause [[otalgia]], ear [[itching]], [[otorrhea]], [[erythema]] and [[edema]] of the [[ear canal]], [[hearing loss]], ear pressure, and [[dermatitis]].<ref name="urlOtitis externa - Symptoms - NHS Choices">{{cite web |url=http://www.nhs.uk/Conditions/otitis-externa/Pages/symptoms.aspx |title=Otitis externa - Symptoms - NHS Choices |format= |work= |accessdate=}}</ref><ref name="urlSwimmers ear : MedlinePlus Medical Encyclopedia">{{cite web |url=https://www.nlm.nih.gov/medlineplus/ency/article/000622.htm |title=Swimmer's ear : MedlinePlus Medical Encyclopedia |format= |work= |accessdate=}}</ref> Malignant otitis externa must be differentiated from other diseases that cause [[facial palsy]], [[osteitis]], [[difficulty swallowing]], and [[hoarseness]].<ref name="urlMalignant otitis externa: MedlinePlus Medical Encyclopedia">{{cite web |url=https://www.nlm.nih.gov/medlineplus/ency/article/000672.htm |title=Malignant otitis externa: MedlinePlus Medical Encyclopedia |format= |work= |accessdate=}}</ref><ref name="pmid12892351">{{cite journal |vauthors=Handzel O, Halperin D |title=Necrotizing (malignant) external otitis |journal=Am Fam Physician |volume=68 |issue=2 |pages=309–12 |year=2003 |pmid=12892351 |doi= |url=}}</ref>
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
|+
! style="background: #4479BA; width: 120px;" | {{fontcolor|#FFF|Disease}}
! style="background: #4479BA; width: 550px;" | {{fontcolor|#FFF|Findings}}
|-
| style="padding: 5px 5px; background: #DCDCDC;" | '''[[EHEC]]'''
| style="padding: 5px 5px; background: #F5F5F5;" | May present with [[fever]], [[chills]] [[vomiting]], [[diarrhea]], generalized [[pain]] or [[malaise]], and gastointestinal bleeding that follow an [[incubation period]] of 3-7 days. Unlike ''E. coli'', ''Shigella'' cannot ferment lactose or decarboxylate lysine.<ref name="NCBI">{{cite journal |last= Hale|first=TL |last2=Keusch|first2=GT |date=1996 |title=Shigella. In: Baron S, editor. Medical Microbiology. 4th edition.  |url=http://www.ncbi.nlm.nih.gov/books/NBK8038/ |journal=Galveston (TX): University of Texas Medical Branch at Galveston|access-date=4 April 2015}}</ref>
|-
| style="padding: 5px 5px; background: #DCDCDC;" | '''[[Ebola]]'''
| style="padding: 5px 5px; background: #F5F5F5;" | Presents with [[fever]], [[chills]] [[vomiting]], [[diarrhea]], generalized [[pain]] or [[malaise]], and sometimes [[Internal bleeding|internal]] and external [[bleeding]], that follow an [[incubation period]] of 2-21 days.
|-
| style="padding: 5px 5px; background: #DCDCDC;" | '''[[Typhoid fever]]'''
| style="padding: 5px 5px; background: #F5F5F5;" | Presents with [[fever]], [[headache]], [[rash]], gastrointestinal symptoms, with [[lymphadenopathy]], relative [[bradycardia]], [[cough]] and [[leucopenia]] and sometimes [[sore throat]]. [[Blood]] and [[stool culture]] can confirm the presence of the causative bacteria.
|-
| style="padding: 5px 5px; background: #DCDCDC;" |'''[[Malaria]]'''
| style="padding: 5px 5px; background: #F5F5F5;" |Presents with acute [[fever]], [[headache]] and sometimes [[diarrhea]] (children). A [[blood smear]]s must be examined for malaria parasites. The presence of [[parasites]] does not exclude a concurrent viral infection. An [[antimalarial]] should be prescribed as an [[empiric therapy]].
|-
| style="padding: 5px 5px; background: #DCDCDC;" | '''[[Lassa fever]]'''
| style="padding: 5px 5px; background: #F5F5F5;" |Disease onset is usually gradual, with [[fever]], [[sore throat]], [[cough]], [[pharyngitis]], and [[facial edema]] in the later stages. [[Inflammation]] and exudation of the [[pharynx]] and [[conjunctiva]] are common.
|-
| style="padding: 5px 5px; background: #DCDCDC;" | '''[[Yellow fever]] and other [[Flaviviridae]] '''
| style="padding: 5px 5px; background: #F5F5F5;" | Present with [[hemorrhage|hemorrhagic]] complications. [[Epidemiological]] investigation may reveal a pattern of disease [[transmission]] by an insect vector. Virus isolation and serological investigation serves to distinguish these [[viruses]]. Confirmed history of previous [[yellow fever]] [[vaccination]] will rule out [[yellow fever]].
|-
| style="padding: 5px 5px; background: #DCDCDC;" | '''Others'''
| style="padding: 5px 5px; background: #F5F5F5;" |[[Viral hepatitis]], [[leptospirosis]], [[rheumatic fever]], [[typhus]], and [[mononucleosis]] can produce [[signs]] and [[symptoms]] that may be confused with [[Ebola]] in the early stages of [[infection]].
|-
|}
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Revision as of 16:25, 9 May 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Overview

Acute otitis externa must be differentiated from other diseases that cause otalgia, ear itching, otorrhea, erythema and edema of the ear canal, hearing loss, ear pressure, and dermatitis. Malignant otitis externa must be differentiated from other diseases that cause facial palsy, osteitis, difficulty swallowing, and hoarseness.

Differentiating Otitis Externa From Other Diseases

Acute otitis externa must be differentiated from other diseases that cause otalgia, ear itching, otorrhea, erythema and edema of the ear canal, hearing loss, ear pressure, and dermatitis.[1][2] Malignant otitis externa must be differentiated from other diseases that cause facial palsy, osteitis, difficulty swallowing, and hoarseness.[3][4]

Disease Findings
EHEC May present with fever, chills vomiting, diarrhea, generalized pain or malaise, and gastointestinal bleeding that follow an incubation period of 3-7 days. Unlike E. coli, Shigella cannot ferment lactose or decarboxylate lysine.[5]
Ebola Presents with fever, chills vomiting, diarrhea, generalized pain or malaise, and sometimes internal and external bleeding, that follow an incubation period of 2-21 days.
Typhoid fever Presents with fever, headache, rash, gastrointestinal symptoms, with lymphadenopathy, relative bradycardia, cough and leucopenia and sometimes sore throat. Blood and stool culture can confirm the presence of the causative bacteria.
Malaria Presents with acute fever, headache and sometimes diarrhea (children). A blood smears must be examined for malaria parasites. The presence of parasites does not exclude a concurrent viral infection. An antimalarial should be prescribed as an empiric therapy.
Lassa fever Disease onset is usually gradual, with fever, sore throat, cough, pharyngitis, and facial edema in the later stages. Inflammation and exudation of the pharynx and conjunctiva are common.
Yellow fever and other Flaviviridae Present with hemorrhagic complications. Epidemiological investigation may reveal a pattern of disease transmission by an insect vector. Virus isolation and serological investigation serves to distinguish these viruses. Confirmed history of previous yellow fever vaccination will rule out yellow fever.
Others Viral hepatitis, leptospirosis, rheumatic fever, typhus, and mononucleosis can produce signs and symptoms that may be confused with Ebola in the early stages of infection.

References

  1. "Otitis externa - Symptoms - NHS Choices".
  2. "Swimmer's ear : MedlinePlus Medical Encyclopedia".
  3. "Malignant otitis externa: MedlinePlus Medical Encyclopedia".
  4. Handzel O, Halperin D (2003). "Necrotizing (malignant) external otitis". Am Fam Physician. 68 (2): 309–12. PMID 12892351.
  5. Hale, TL; Keusch, GT (1996). "Shigella. In: Baron S, editor. Medical Microbiology. 4th edition". Galveston (TX): University of Texas Medical Branch at Galveston. Retrieved 4 April 2015.

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