Intraocular lymphoma

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Evidence Based Medicine
Cochrane Collaboration on Intraocular lymphoma Bandolier on Intraocular lymphoma TRIP on Intraocular lymphoma
Clinical Trials
Ongoing Trials on Intraocular lymphoma at Clinical Trials.gov Trial results on Intraocular lymphoma Clinical Trials on Intraocular lymphoma at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Intraocular lymphoma NICE Guidance on Intraocular lymphoma NHS PRODIGY Guidance FDA on Intraocular lymphoma CDC on Intraocular lymphoma
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Commentary
Blogs on Intraocular lymphoma
Definitions
Definitions of Intraocular lymphoma
Patient Resources / Community
Patient resources on Intraocular lymphoma Discussion groups on Intraocular lymphoma Patient Handouts on Intraocular lymphoma Directions to Hospitals Treating Intraocular lymphoma Risk calculators and risk factors for Intraocular lymphoma
Healthcare Provider Resources
Symptoms of Intraocular lymphoma Causes & Risk Factors for Intraocular lymphoma Diagnostic studies for Intraocular lymphoma Treatment of Intraocular lymphoma
Continuing Medical Education (CME)
CME Programs on Intraocular lymphoma
International
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Experimental / Informatics
List of terms related to Intraocular lymphoma

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Synonyms and keywords: Synonym 1; Synonym 2; Synonym 3

Historical Perspective

• Intraocular lymphoma was first discovered by [scientist name], a [nationality + occupation], in [year] during/following [event].

Classification

• Intraocular lymphoma may be classified according to [classification method] into [number] subtypes/groups:

• [group1]
• [group2]
• [group3]

Pathophysiology

• The pathogenesis of intraocular lymphoma is characterized by
• Genes associated with the development of intraocular lymphoma, include:
• On gross pathology, characteristic findings of intraocular lymphoma, include:
• On microscopic histopathological analysis, characteristic findings of intraocular lymphoma, include:

Causes

• Common causes of intraocular lymphoma, include:

Differentiating Intraocular Lymphoma from Other Diseases

• Intraocular lymphoma must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as:

• [Differential dx1]
• [Differential dx2]
• [Differential dx3]

Epidemiology and Demographics

• The prevalence of intraocular lymphoma is approximately [number or range] per 100,000 individuals worldwide.
• In [year], the incidence of intraocular lymphoma was estimated to be [number or range] cases per 100,000 individuals in [location].

Age

• Patients of all age groups may develop intraocular lymphoma.

• Intraocular lymphoma is more commonly observed among patients aged [age range] years old.
• Intraocular lymphoma is more commonly observed among [elderly patients/young patients/children].

Gender

• Intraocular lymphoma affects men and women equally.

• [Gender 1] are more commonly affected with intraocular lymphoma than [gender 2].
• The [gender 1] to [Gender 2] ratio is approximately [number > 1] to 1.

Race

• There is no racial predilection for intraocular lymphoma.

• Intraocular lymphoma usually affects individuals of the [race 1] race.
• [Race 2] individuals are less likely to develop intraocular lymphoma.

Risk Factors

• Common risk factors in the development of intraocular lymphoma, include:

Natural History, Complications and Prognosis

• The majority of patients with intraocular lymphoma remain asymptomatic for [duration/years].
• Early clinical features include [manifestation 1], [manifestation 2], and [manifestation 3].
• If left untreated, [#%] of patients with intraocular lymphoma may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
• Common complications of intraocular lymphoma include [complication 1], [complication 2], and [complication 3].
• Prognosis is generally [excellent/good/poor], and the [1/5/10­year mortality/survival rate] of patients with intraocular lymphoma is approximately [#%].

Diagnosis

Diagnostic Criteria

• The diagnosis of intraocular lymphoma is made when at least [number] of the following [number] diagnostic criteria are met:

• [criterion 1]
• [criterion 2]
• [criterion 3]
• [criterion 4]

Symptoms

• Intraocular lymphoma is usually asymptomatic.
• Symptoms of intraocular lymphoma may include the following:

• [symptom 1]
• [symptom 2]
• [symptom 3]
• [symptom 4]
• [symptom 5]
• [symptom 6]

Physical Examination

• Patients with intraocular lymphoma usually appear [general appearance].
• Physical examination may be remarkable for:

• [finding 1]
• [finding 2]
• [finding 3]
• [finding 4]
• [finding 5]
• [finding 6]

Laboratory Findings

• There are no specific laboratory findings associated with intraocular lymphoma.

• A [positive/negative] [test name] is diagnostic of intraocular lymphoma.
• An [elevated/reduced] concentration of [serum/blood/urinary/CSF/other] [lab test] is diagnostic of intraocular lymphoma.
• Other laboratory findings consistent with the diagnosis of intraocular lymphoma include [abnormal test 1], [abnormal test 2], and [abnormal test 3].

Imaging Findings

• There are no [imaging study] findings associated with intraocular lymphoma.

• [Imaging study 1] is the imaging modality of choice for intraocular lymphoma.
• On [imaging study 1], intraocular lymphoma is characterized by [finding 1], [finding 2], and [finding 3].
• [Imaging study 2] may demonstrate [finding 1], [finding 2], and [finding 3].

Other Diagnostic Studies

• Intraocular lymphoma may also be diagnosed using [diagnostic study name].
• Findings on [diagnostic study name] include [finding 1], [finding 2], and [finding 3].

Treatment

Medical Therapy

• There is no treatment for intraocular lymphoma; the mainstay of therapy is supportive care.

• The mainstay of therapy for intraocular lymphoma is [medical therapy 1] and [medical therapy 2].
• [Medical therapy 1] acts by [mechanism of action1].
• Response to [medical therapy 1] can be monitored with [test/physical finding/imaging] every [frequency/duration].

Surgery

• Surgery is the mainstay of therapy for intraocular lymphoma.
• [Surgical procedure] in conjunction with [chemotherapy/radiation] is the most common approach to the treatment of intraocular lymphoma.
• [Surgical procedure] can only be performed for patients with [disease stage] intraocular lymphoma.

Prevention

• There are no primary preventive measures available for intraocular lymphoma.

• Effective measures for the primary prevention of intraocular lymphoma include [measure1], [measure2], and [measure3].

• Once diagnosed and successfully treated, patients with intraocular lymphoma are followed-up every [duration]. Follow-up testing includes [test 1], [test 2], and [test 3].