Sandbox: Verrucous carcinoma: Difference between revisions
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Created page with "__NOTOC__ {{SI}} {{CMG}} {{AE}} {{MV}} {{SK}} Synonym 1; Synonym 2; Synonym 3 ==Overview== ==Historic..." |
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==Historical Perspective== | ==Historical Perspective== | ||
*Verrucous carcinoma was first discovered by [scientist name], a [nationality + occupation], in [year] during/following [event]. | *Verrucous carcinoma was first discovered by [scientist name], a [nationality + occupation], in [year] during/following [event]. | ||
==Classification== | ==Classification== | ||
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==Pathophysiology== | ==Pathophysiology== | ||
*The pathogenesis of verrucous carcinoma is characterized by | *The pathogenesis of verrucous carcinoma is characterized by | ||
*The [gene name] gene/Mutation in [gene name] has been associated with the development of verrucous carcinoma, involving the [molecular pathway] pathway. | *The [gene name] gene/Mutation in [gene name] has been associated with the development of verrucous carcinoma, involving the [molecular pathway] pathway. | ||
*On gross pathology, | *On gross pathology, characteristic findings of verrucous carcinoma include: | ||
*On microscopic histopathological analysis, | *On microscopic histopathological analysis, characteristic findings of verrucous carcinoma include: | ||
==Causes== | ==Causes== | ||
* | * Common causes of verrucous carcinoma, include: | ||
==Differentiating | ==Differentiating Verrucous Carcinoma from Other Diseases== | ||
*Verrucous carcinoma must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as: | *Verrucous carcinoma must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as: | ||
:*[Differential dx1] | :*[Differential dx1] | ||
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*Patients of all age groups may develop verrucous carcinoma. | *Patients of all age groups may develop verrucous carcinoma. | ||
*Verrucous carcinoma is more commonly observed among patients aged | *Verrucous carcinoma is more commonly observed among patients aged 50 to 80 years old. | ||
*Verrucous carcinoma is more commonly observed among [elderly patients/young patients/children]. | *Verrucous carcinoma is more commonly observed among [elderly patients/young patients/children]. | ||
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*[Gender 1] are more commonly affected with verrucous carcinoma than [gender 2]. | *[Gender 1] are more commonly affected with verrucous carcinoma than [gender 2]. | ||
* The [gender 1] to [Gender 2] ratio is approximately [number > 1] to 1. | *The [gender 1] to [Gender 2] ratio is approximately [number > 1] to 1. | ||
===Race=== | ===Race=== | ||
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==Risk Factors== | ==Risk Factors== | ||
*Common risk factors in the development of verrucous carcinoma | *Common risk factors in the development of verrucous carcinoma, include: | ||
== Natural History, Complications and Prognosis== | == Natural History, Complications and Prognosis== | ||
*The majority of patients with verrucous carcinoma remain asymptomatic for [duration/years]. | *The majority of patients with verrucous carcinoma remain asymptomatic for [duration/years]. | ||
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== Diagnosis == | == Diagnosis == | ||
===Diagnostic Criteria=== | ===Diagnostic Criteria=== | ||
*The diagnosis of verrucous carcinoma is made | *The diagnosis of verrucous carcinoma is made with the following diagnostic criteria: | ||
:*[criterion 1] | :*[criterion 1] | ||
:*[criterion 2] | :*[criterion 2] | ||
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:*[symptom 2] | :*[symptom 2] | ||
:*[symptom 3] | :*[symptom 3] | ||
=== Physical Examination === | === Physical Examination === | ||
*Patients with verrucous carcinoma usually appear | *Patients with verrucous carcinoma usually appear malnourished. | ||
*Physical examination may be remarkable for: | *Physical examination may be remarkable for: | ||
:*[finding 1] | :*[finding 1] | ||
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*There are no specific laboratory findings associated with verrucous carcinoma. | *There are no specific laboratory findings associated with verrucous carcinoma. | ||
===Imaging Findings=== | |||
===Imaging Findings=== | |||
*[Imaging study 1] is the imaging modality of choice for verrucous carcinoma. | *[Imaging study 1] is the imaging modality of choice for verrucous carcinoma. | ||
*On [imaging study 1], verrucous carcinoma is characterized by [finding 1], [finding 2], and [finding 3]. | *On [imaging study 1], verrucous carcinoma is characterized by [finding 1], [finding 2], and [finding 3]. | ||
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== Treatment == | == Treatment == | ||
=== Medical Therapy === | === Medical Therapy === | ||
*The mainstay of therapy for verrucous carcinoma, includes: | |||
*The mainstay of therapy for verrucous carcinoma | |||
=== Surgery === | === Surgery === | ||
*Surgery is the mainstay of therapy for verrucous carcinoma. | *Surgery is the mainstay of therapy for verrucous carcinoma. | ||
*[Surgical procedure] in conjunction with [chemotherapy/radiation] is the most common approach to the treatment of verrucous carcinoma. | *[Surgical procedure] in conjunction with [chemotherapy/radiation] is the most common approach to the treatment of verrucous carcinoma. | ||
=== Prevention === | === Prevention === | ||
*There are no primary preventive measures available for verrucous carcinoma. | *There are no primary preventive measures available for verrucous carcinoma. | ||
Revision as of 13:29, 11 May 2016
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Synonyms and keywords: Synonym 1; Synonym 2; Synonym 3
Overview
Historical Perspective
- Verrucous carcinoma was first discovered by [scientist name], a [nationality + occupation], in [year] during/following [event].
Classification
- Verrucous carcinoma may be classified according to [classification method] into [number] subtypes/groups:
- [group1]
- [group2]
- [group3]
- Other variants of verrucous carcinoma include [disease subtype 1], [disease subtype 2], and [disease subtype 3].
Pathophysiology
- The pathogenesis of verrucous carcinoma is characterized by
- The [gene name] gene/Mutation in [gene name] has been associated with the development of verrucous carcinoma, involving the [molecular pathway] pathway.
- On gross pathology, characteristic findings of verrucous carcinoma include:
- On microscopic histopathological analysis, characteristic findings of verrucous carcinoma include:
Causes
- Common causes of verrucous carcinoma, include:
Differentiating Verrucous Carcinoma from Other Diseases
- Verrucous carcinoma must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as:
- [Differential dx1]
- [Differential dx2]
- [Differential dx3]
Epidemiology and Demographics
- The prevalence of verrucous carcinoma is approximately [number or range] per 100,000 individuals worldwide.
- In [year], the incidence of verrucous carcinoma was estimated to be [number or range] cases per 100,000 individuals in [location].
Age
- Patients of all age groups may develop verrucous carcinoma.
- Verrucous carcinoma is more commonly observed among patients aged 50 to 80 years old.
- Verrucous carcinoma is more commonly observed among [elderly patients/young patients/children].
Gender
- Verrucous carcinoma affects men and women equally.
- [Gender 1] are more commonly affected with verrucous carcinoma than [gender 2].
- The [gender 1] to [Gender 2] ratio is approximately [number > 1] to 1.
Race
- There is no racial predilection for verrucous carcinoma.
- Verrucous carcinoma usually affects individuals of the [race 1] race.
- [Race 2] individuals are less likely to develop verrucous carcinoma.
Risk Factors
- Common risk factors in the development of verrucous carcinoma, include:
Natural History, Complications and Prognosis
- The majority of patients with verrucous carcinoma remain asymptomatic for [duration/years].
- Early clinical features include [manifestation 1], [manifestation 2], and [manifestation 3].
- If left untreated, [#%] of patients with verrucous carcinoma may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
- Common complications of verrucous carcinoma include [complication 1], [complication 2], and [complication 3].
- Prognosis is generally [excellent/good/poor], and the [1/5/10year mortality/survival rate] of patients with verrucous carcinoma is approximately [#%].
Diagnosis
Diagnostic Criteria
- The diagnosis of verrucous carcinoma is made with the following diagnostic criteria:
- [criterion 1]
- [criterion 2]
- [criterion 3]
- [criterion 4]
Symptoms
- Verrucous carcinoma is usually asymptomatic.
- Symptoms of verrucous carcinoma may include the following:
- [symptom 1]
- [symptom 2]
- [symptom 3]
Physical Examination
- Patients with verrucous carcinoma usually appear malnourished.
- Physical examination may be remarkable for:
- [finding 1]
- [finding 2]
- [finding 3]
- [finding 4]
- [finding 5]
- [finding 6]
Laboratory Findings
- There are no specific laboratory findings associated with verrucous carcinoma.
Imaging Findings
- [Imaging study 1] is the imaging modality of choice for verrucous carcinoma.
- On [imaging study 1], verrucous carcinoma is characterized by [finding 1], [finding 2], and [finding 3].
- [Imaging study 2] may demonstrate [finding 1], [finding 2], and [finding 3].
Other Diagnostic Studies
- Verrucous carcinoma may also be diagnosed using [diagnostic study name].
- Findings on [diagnostic study name] include [finding 1], [finding 2], and [finding 3].
Treatment
Medical Therapy
- The mainstay of therapy for verrucous carcinoma, includes:
Surgery
- Surgery is the mainstay of therapy for verrucous carcinoma.
- [Surgical procedure] in conjunction with [chemotherapy/radiation] is the most common approach to the treatment of verrucous carcinoma.
Prevention
- There are no primary preventive measures available for verrucous carcinoma.
- Effective measures for the primary prevention of verrucous carcinoma include [measure1], [measure2], and [measure3].
- Once diagnosed and successfully treated, patients with verrucous carcinoma are followed-up every [duration]. Follow-up testing includes [test 1], [test 2], and [test 3].