Cogan syndrome: Difference between revisions
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'''Cogan syndrome''' is a rare disorder characterized by recurrent inflammation of the front of the eye (the cornea) and often fever, fatigue, and weight loss, episodes of dizziness, and hearing loss. It can lead to deafness or blindness if untreated. The classic form of the disease was first described by D.G. Cogan in 1945. | '''Cogan syndrome''' is a rare disorder characterized by recurrent inflammation of the front of the eye (the cornea) and often fever, fatigue, and weight loss, episodes of dizziness, and hearing loss. It can lead to deafness or blindness if untreated. The classic form of the disease was first described by D.G. Cogan in 1945. | ||
== | ==Historical Perspective== | ||
In 1945 D.G. Cogan first described the "nonsyphilitic interstitial keratitis and vestibuloauditory symptoms" that would later bear his name (Cogan, 1945). In 1963, the atypical form of Cogan syndrome was first described (Bennett, 1963) | In 1945 D.G. Cogan first described the "nonsyphilitic interstitial keratitis and vestibuloauditory symptoms" that would later bear his name (Cogan, 1945). In 1963, the atypical form of Cogan syndrome was first described (Bennett, 1963) | ||
==Classification== | |||
==Pathophysiology== | |||
==Causes== | |||
==Differentiating Cogan Syndrome from other Diseases== | |||
==Epidemiology and Demographics== | |||
==Risk Factors== | |||
==Natural History, Complications and Prognosis== | |||
==Diagnosis== | |||
===Diagnostic Criteria=== | |||
===Symptoms=== | |||
===Physical Examination=== | |||
===Laboratory Findings=== | |||
===Imaging Findings=== | |||
===Other Diagnostic Studies=== | |||
==Treatment== | |||
===Medical Therapy=== | |||
===Surgery=== | |||
===Prevention | |||
==Related disorders== | ==Related disorders== | ||
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==References== | ==References== | ||
{{Reflist|2}} | |||
* {{cite journal | author=Cogan DG | title=Syndrome of nonsyphilitic interstitial keratitis and vestiboloauditory symptoms | journal=Arch Ophthalmol | year=1945 | pages=144–9 | volume=33 }} | * {{cite journal | author=Cogan DG | title=Syndrome of nonsyphilitic interstitial keratitis and vestiboloauditory symptoms | journal=Arch Ophthalmol | year=1945 | pages=144–9 | volume=33 }} | ||
* {{cite journal | author=Bennett FM | title=Bilateral recurrent episcleritis associated with posterior corneal changes, vestibulo-auditory symptoms and rheumatoid arthritis | journal=Am J Ophthalmol | year=1963 | pages=815-8 | volume=55 }} PMID 13967466 | * {{cite journal | author=Bennett FM | title=Bilateral recurrent episcleritis associated with posterior corneal changes, vestibulo-auditory symptoms and rheumatoid arthritis | journal=Am J Ophthalmol | year=1963 | pages=815-8 | volume=55 }} PMID 13967466 | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Synonyms and keywords: Oculovestibuloauditory syndrome
Overview
Cogan syndrome is a rare disorder characterized by recurrent inflammation of the front of the eye (the cornea) and often fever, fatigue, and weight loss, episodes of dizziness, and hearing loss. It can lead to deafness or blindness if untreated. The classic form of the disease was first described by D.G. Cogan in 1945.
Historical Perspective
In 1945 D.G. Cogan first described the "nonsyphilitic interstitial keratitis and vestibuloauditory symptoms" that would later bear his name (Cogan, 1945). In 1963, the atypical form of Cogan syndrome was first described (Bennett, 1963)
Classification
Pathophysiology
Causes
Differentiating Cogan Syndrome from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Criteria
Symptoms
Physical Examination
Laboratory Findings
Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
===Prevention
Related disorders
References
- Cogan DG (1945). "Syndrome of nonsyphilitic interstitial keratitis and vestiboloauditory symptoms". Arch Ophthalmol. 33: 144–9.
- Bennett FM (1963). "Bilateral recurrent episcleritis associated with posterior corneal changes, vestibulo-auditory symptoms and rheumatoid arthritis". Am J Ophthalmol. 55: 815–8. PMID 13967466