Heparin-induced thrombocytopenia historical perspective: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Heparin-induced thrombocytopenia}} | {{Heparin-induced thrombocytopenia}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{shyam}} | ||
==Overview== | ==Overview== | ||
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==Historical Perspective== | ==Historical Perspective== | ||
*In the 1950s, Rodger Weissman and Richard Tobin of Hitchcock Memorial Hospital and Dartmouth Medical School describes the phenomenon of HIT.<ref name="pmidPMID13497418">{{cite journal| author=WEISMANN RE, TOBIN RW| title=Arterial embolism occurring during systemic heparin therapy. | journal=AMA Arch Surg | year= 1958 | volume= 76 | issue= 2 | pages= 219-25; discussion 225-7 | pmid=PMID13497418 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13497418 }} </ref> <ref name="pmid23714311">{{cite journal| author=Lee GM, Arepally GM| title=Diagnosis and management of heparin-induced thrombocytopenia. | journal=Hematol Oncol Clin North Am | year= 2013 | volume= 27 | issue= 3 | pages= 541-63 | pmid=23714311 | doi=10.1016/j.hoc.2013.02.001 | pmc=3668315 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23714311 }} </ref> They noted an alarming increase in the incidence of peripheral arterial embolism after systemic heparin therapy.<ref name="pmidPMID13497418">{{cite journal| author=WEISMANN RE, TOBIN RW| title=Arterial embolism occurring during systemic heparin therapy. | journal=AMA Arch Surg | year= 1958 | volume= 76 | issue= 2 | pages= 219-25; discussion 225-7 | pmid=PMID13497418 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13497418 }} </ref> They reported 10 cases of embolism and thrombotic complications after heparin. <ref name="pmidPMID13497418">{{cite journal| author=WEISMANN RE, TOBIN RW| title=Arterial embolism occurring during systemic heparin therapy. | journal=AMA Arch Surg | year= 1958 | volume= 76 | issue= 2 | pages= 219-25; discussion 225-7 | pmid=PMID13497418 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13497418 }} </ref> Emboli were noted in the femoral, popliteal, and cerebral circulation. This seminal study paved the way for future investigations into the pathophysiology of HIT. | |||
==References== | ==References== | ||
Revision as of 18:31, 6 July 2017
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Heparin-induced thrombocytopenia |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shyam Patel [2]
Overview
Historical Perspective
- In the 1950s, Rodger Weissman and Richard Tobin of Hitchcock Memorial Hospital and Dartmouth Medical School describes the phenomenon of HIT.[1] [2] They noted an alarming increase in the incidence of peripheral arterial embolism after systemic heparin therapy.[1] They reported 10 cases of embolism and thrombotic complications after heparin. [1] Emboli were noted in the femoral, popliteal, and cerebral circulation. This seminal study paved the way for future investigations into the pathophysiology of HIT.
References
- ↑ 1.0 1.1 1.2 WEISMANN RE, TOBIN RW (1958). "Arterial embolism occurring during systemic heparin therapy". AMA Arch Surg. 76 (2): 219–25, discussion 225-7. PMID PMID13497418 Check
|pmid=value (help). - ↑ Lee GM, Arepally GM (2013). "Diagnosis and management of heparin-induced thrombocytopenia". Hematol Oncol Clin North Am. 27 (3): 541–63. doi:10.1016/j.hoc.2013.02.001. PMC 3668315. PMID 23714311.