Rheumatoid arthritis overview: Difference between revisions
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==Historical Perspective== | ==Historical Perspective== | ||
[[Rheumatoid arthritis]] signs and symptoms are noticed by Augustin Jacob Landre-Beauvais, a resident physician at the Saltpetriere asylum in France, in 1800, He named it as Goutte Asthenique Primitive or Primary Asthenic [[Gout]]. The name [[Rheumatoid arthritis]] coined by Archibald Garrod in 1890. [[HLA-DR]] locus present on [[chromosome]] 6 is involved in the pathogenesis of rheumatoid arthritis. | |||
==Classification== | ==Classification== | ||
Revision as of 14:11, 10 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Rheumatoid arthritis (RA) is traditionally considered a chronic, inflammatoryautoimmune disorder that causes the immune system to attack the joints. It is a disabling and painful inflammatory condition, which can lead to substantial loss of mobility due to pain and joint destruction. RA is a systemic disease, often affecting extra-articular tissues throughout the body including the skin, blood vessels, heart, lungs, and muscles.
The name is derived from the Greek word rheumatos which means "flowing", and this initially gave rise to the term 'rheumatic fever', an illness that can follow throat infections and which includes joint pain. The suffix -oid means "resembling", i.e. resembling rheumatic fever. Arthr means "joint" and the suffix -itis, a "condition involving inflammation". Thus, rheumatoid arthritis was a form of joint inflammation that resembled rheumatic fever. Rheumatoid arthritis appears to have been described in paintings more than a century before the first detailed medical description of the condition in 1800 by Landre-Beauvais.[1]
Historical Perspective
Rheumatoid arthritis signs and symptoms are noticed by Augustin Jacob Landre-Beauvais, a resident physician at the Saltpetriere asylum in France, in 1800, He named it as Goutte Asthenique Primitive or Primary Asthenic Gout. The name Rheumatoid arthritis coined by Archibald Garrod in 1890. HLA-DR locus present on chromosome 6 is involved in the pathogenesis of rheumatoid arthritis.