Thrombophilia differential diagnosis: Difference between revisions
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==Differential Diagnosis== | ==Differential Diagnosis== | ||
*Inherited thrombophilias should be suspected in following clinical presentations: | *Inherited thrombophilias should be suspected in following clinical presentations<ref name=?>DeLoughery TG. Hemostasis and Thrombosis: Springer International Publishing; 2014.</ref>: | ||
**Family history of thrombosis, especially at an early age | **Family history of thrombosis, especially at an early age | ||
**Unprovoked thrombosis at an early age (<40-55 for venous thrombosis and <50-55 for arterial thrombosis) | **Unprovoked thrombosis at an early age (<40-55 for venous thrombosis and <50-55 for arterial thrombosis) | ||
Revision as of 21:03, 24 June 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Asiri Ediriwickrema, M.D., M.H.S. [2]
Overview
- Inherited thrombophilia must be differentiated from acquired thrombophilia, as it may influence the selection and duration of anticoagulation.
- Inherited thrombophilias should be suspected in patients with the certain clinical presentations[1].
- Screening for inherited thrombophilias is controversial and should be performed in the appropriate clinical context.
Differential Diagnosis
- Inherited thrombophilias should be suspected in following clinical presentations[2]:
- Family history of thrombosis, especially at an early age
- Unprovoked thrombosis at an early age (<40-55 for venous thrombosis and <50-55 for arterial thrombosis)
- Recurrent thrombosis
- Thrombosis at multiple sites, or unusual locations including in cerebral, splanchnic, and renal veins.
- Thrombosis in arteries with the abscence of arterial disease
- History of fetal loss
References
- ↑ Cohoon KP, Heit JA (2014). "Inherited and secondary thrombophilia". Circulation. 129 (2): 254–7. doi:10.1161/CIRCULATIONAHA.113.001943. PMC 3979345. PMID 24421360.
- ↑ DeLoughery TG. Hemostasis and Thrombosis: Springer International Publishing; 2014.