Hashimoto's thyroiditis laboratory findings: Difference between revisions
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== Laboratory Findings == | == Laboratory Findings == | ||
=== | ===Thyroid hormones=== | ||
* [[Thyroid-stimulating hormone]] (TSH) | * [[Thyroid-stimulating hormone]] (TSH) | ||
* Free [[T3]] and Free [[T4]] | * Free [[T3]] and Free [[T4]] | ||
===Thyroid antibodies=== | |||
* Anti-thyroid peroxidase antibodies (anti-TPO) | |||
* Anti-thyroglobulin antibodies (anti-Tg) | * Anti-thyroglobulin antibodies (anti-Tg) | ||
* Anti-microsomal antibodies can help obtain an accurate diagnosis.<ref>{{cite book |last1= Giannini |first1= AJ |authorlink1= |title= The Biological Foundations of Clinical Psychiatry |url= |year= 1986 |publisher= Medical Examination Publishing Company |location= New Hyde Park, NY |language= |isbn= 0-87488-449-7 |oclc= |doi= |id= |page= |pages= 193–198 |quote= |ref= |bibcode= }}</ref> Earlier assessment of the patient may present with elevated levels of thyroglobulin owing to the transient [[thyrotoxicosis]] as inflammation within the thyroid causes damage to the integrity of thyroid follicle storage of thyroglobulin; TSH is concomitantly decreased.<ref>{{cite journal|last=Simmons|first=PJ|coauthors=Dellemarre, FG., Drexhage, HA.|title=Antigen-presenting dendritic cells as regulators of the growth of thyrocytes: a role of interleukin-1beta and interleukin-6|journal=Endocrinology|year=1998|month=July|volume=139|issue=7|pages=3158–3186|pmid=9645688|doi=10.1210/en.139.7.3148}}</ref> | * Anti-microsomal antibodies can help obtain an accurate diagnosis.<ref>{{cite book |last1= Giannini |first1= AJ |authorlink1= |title= The Biological Foundations of Clinical Psychiatry |url= |year= 1986 |publisher= Medical Examination Publishing Company |location= New Hyde Park, NY |language= |isbn= 0-87488-449-7 |oclc= |doi= |id= |page= |pages= 193–198 |quote= |ref= |bibcode= }}</ref> Earlier assessment of the patient may present with elevated levels of thyroglobulin owing to the transient [[thyrotoxicosis]] as inflammation within the thyroid causes damage to the integrity of thyroid follicle storage of thyroglobulin; TSH is concomitantly decreased.<ref>{{cite journal|last=Simmons|first=PJ|coauthors=Dellemarre, FG., Drexhage, HA.|title=Antigen-presenting dendritic cells as regulators of the growth of thyrocytes: a role of interleukin-1beta and interleukin-6|journal=Endocrinology|year=1998|month=July|volume=139|issue=7|pages=3158–3186|pmid=9645688|doi=10.1210/en.139.7.3148}}</ref> | ||
* Diagnosis is made by detecting elevated levels of Anti-TPO antibodies in the serum. | * Diagnosis is made by detecting elevated levels of Anti-TPO antibodies in the serum. | ||
Revision as of 17:43, 19 July 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory Findings
Thyroid hormones
- Thyroid-stimulating hormone (TSH)
- Free T3 and Free T4
Thyroid antibodies
- Anti-thyroid peroxidase antibodies (anti-TPO)
- Anti-thyroglobulin antibodies (anti-Tg)
- Anti-microsomal antibodies can help obtain an accurate diagnosis.[1] Earlier assessment of the patient may present with elevated levels of thyroglobulin owing to the transient thyrotoxicosis as inflammation within the thyroid causes damage to the integrity of thyroid follicle storage of thyroglobulin; TSH is concomitantly decreased.[2]
- Diagnosis is made by detecting elevated levels of Anti-TPO antibodies in the serum.
References
- ↑ Giannini, AJ (1986). The Biological Foundations of Clinical Psychiatry. New Hyde Park, NY: Medical Examination Publishing Company. pp. 193–198. ISBN 0-87488-449-7.
- ↑ Simmons, PJ (1998). "Antigen-presenting dendritic cells as regulators of the growth of thyrocytes: a role of interleukin-1beta and interleukin-6". Endocrinology. 139 (7): 3158–3186. doi:10.1210/en.139.7.3148. PMID 9645688. Unknown parameter
|month=ignored (help); Unknown parameter|coauthors=ignored (help)