Hypoglycemia epidemiology and demographics: Difference between revisions
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==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
* Patients with type 1 diabetes may suffer an average of two episodes of symptomatic hypoglycemia per week thousands of such episodes over a lifetime of diabetes, and one episode of severe, at least temporarily disabling hypoglycemia per year. | |||
* Severe hypoglycemia events have been reported to range from 62 to 320 episodes per 100 patient years in type 1 diabetes.<ref name="pmid17415551">{{cite journal| author=UK Hypoglycaemia Study Group| title=Risk of hypoglycaemia in types 1 and 2 diabetes: effects of treatment modalities and their duration. | journal=Diabetologia | year= 2007 | volume= 50 | issue= 6 | pages= 1140-7 | pmid=17415551 | doi=10.1007/s00125-007-0599-y | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17415551 }}</ref> | |||
* Hypoglycemia is less frequent in type 2 diabetes than it is in type1.<ref name="pmid19033403">{{cite journal| author=Cryer PE| title=The barrier of hypoglycemia in diabetes. | journal=Diabetes | year= 2008 | volume= 57 | issue= 12 | pages= 3169-76 | pmid=19033403 | doi=10.2337/db08-1084 | pmc=2584119 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19033403 }}</ref> | |||
* Event rate for severe in insulin-treated type 2 diabetes is approximately 30 percent of that in type 1.<ref name="pmid15910627">{{cite journal| author=Donnelly LA, Morris AD, Frier BM, Ellis JD, Donnan PT, Durrant R et al.| title=Frequency and predictors of hypoglycaemia in Type 1 and insulin-treated Type 2 diabetes: a population-based study. | journal=Diabet Med | year= 2005 | volume= 22 | issue= 6 | pages= 749-55 | pmid=15910627 | doi=10.1111/j.1464-5491.2005.01501.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15910627 }}</ref> | |||
* Event rates for hypoglycemia requiring professional emergency medical treatment range from 40 to 100 percent of those in type 1 diabetes.<ref name="pmid12663593">{{cite journal| author=Leese GP, Wang J, Broomhall J, Kelly P, Marsden A, Morrison W et al.| title=Frequency of severe hypoglycemia requiring emergency treatment in type 1 and type 2 diabetes: a population-based study of health service resource use. | journal=Diabetes Care | year= 2003 | volume= 26 | issue= 4 | pages= 1176-80 | pmid=12663593 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12663593 }}</ref> | |||
* Frequency of hypoglycemia in patients with type 2 diabetes approaches that in type 1 diabetes as patients with type 2 diabetes approach the insulin deficient end of the spectrum of the disease and require aggressive treatment with insulin.<ref name="pmid190334032">{{cite journal| author=Cryer PE| title=The barrier of hypoglycemia in diabetes. | journal=Diabetes | year= 2008 | volume= 57 | issue= 12 | pages= 3169-76 | pmid=19033403 | doi=10.2337/db08-1084 | pmc=2584119 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19033403 }}</ref> | |||
* Hypoglycemia is uncommon in individuals who do not have drug-treated diabetes mellitus.<ref name="pmid10500928">{{cite journal| author=Service FJ| title=Classification of hypoglycemic disorders. | journal=Endocrinol Metab Clin North Am | year= 1999 | volume= 28 | issue= 3 | pages= 501-17, vi | pmid=10500928 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10500928 }}</ref> | |||
==References== | ==References== |
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Overview
Epidemiology and Demographics
- Patients with type 1 diabetes may suffer an average of two episodes of symptomatic hypoglycemia per week thousands of such episodes over a lifetime of diabetes, and one episode of severe, at least temporarily disabling hypoglycemia per year.
- Severe hypoglycemia events have been reported to range from 62 to 320 episodes per 100 patient years in type 1 diabetes.[1]
- Hypoglycemia is less frequent in type 2 diabetes than it is in type1.[2]
- Event rate for severe in insulin-treated type 2 diabetes is approximately 30 percent of that in type 1.[3]
- Event rates for hypoglycemia requiring professional emergency medical treatment range from 40 to 100 percent of those in type 1 diabetes.[4]
- Frequency of hypoglycemia in patients with type 2 diabetes approaches that in type 1 diabetes as patients with type 2 diabetes approach the insulin deficient end of the spectrum of the disease and require aggressive treatment with insulin.[5]
- Hypoglycemia is uncommon in individuals who do not have drug-treated diabetes mellitus.[6]
References
- ↑ UK Hypoglycaemia Study Group (2007). "Risk of hypoglycaemia in types 1 and 2 diabetes: effects of treatment modalities and their duration". Diabetologia. 50 (6): 1140–7. doi:10.1007/s00125-007-0599-y. PMID 17415551.
- ↑ Cryer PE (2008). "The barrier of hypoglycemia in diabetes". Diabetes. 57 (12): 3169–76. doi:10.2337/db08-1084. PMC 2584119. PMID 19033403.
- ↑ Donnelly LA, Morris AD, Frier BM, Ellis JD, Donnan PT, Durrant R; et al. (2005). "Frequency and predictors of hypoglycaemia in Type 1 and insulin-treated Type 2 diabetes: a population-based study". Diabet Med. 22 (6): 749–55. doi:10.1111/j.1464-5491.2005.01501.x. PMID 15910627.
- ↑ Leese GP, Wang J, Broomhall J, Kelly P, Marsden A, Morrison W; et al. (2003). "Frequency of severe hypoglycemia requiring emergency treatment in type 1 and type 2 diabetes: a population-based study of health service resource use". Diabetes Care. 26 (4): 1176–80. PMID 12663593.
- ↑ Cryer PE (2008). "The barrier of hypoglycemia in diabetes". Diabetes. 57 (12): 3169–76. doi:10.2337/db08-1084. PMC 2584119. PMID 19033403.
- ↑ Service FJ (1999). "Classification of hypoglycemic disorders". Endocrinol Metab Clin North Am. 28 (3): 501–17, vi. PMID 10500928.