Differentiating Metabolic syndrome from other diseases: Difference between revisions
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==Differentiating Metabolic Syndrome from other Diseases== | ==Differentiating Metabolic Syndrome from other Diseases== | ||
The table below summarizes the findings that differentiate Cushing's disease from other conditions that may cause [[Hypertension|hypertensio]]<nowiki/>n, [[hyperandrogenism]], and [[obesity]]. Facial plethora, skin changes, [[osteoporosis]], [[nephrolithiasis]] and neuropsychiatric conditions should raise the concern for Cushing's syndrome.<ref name="pmid11253984">{{cite journal |vauthors=Boscaro M, Barzon L, Fallo F, Sonino N |title=Cushing's syndrome |journal=Lancet |volume=357 |issue=9258 |pages=783–91 |year=2001 |pmid=11253984 |doi=10.1016/S0140-6736(00)04172-6 |url=}}</ref><ref name="pmid11571938">{{cite journal |vauthors=Findling JW, Raff H |title=Diagnosis and differential diagnosis of Cushing's syndrome |journal=Endocrinol. Metab. Clin. North Am. |volume=30 |issue=3 |pages=729–47 |year=2001 |pmid=11571938 |doi= |url=}}</ref><ref name="pmid9793762">{{cite journal |vauthors=Newell-Price J, Trainer P, Besser M, Grossman A |title=The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states |journal=Endocr. Rev. |volume=19 |issue=5 |pages=647–72 |year=1998 |pmid=9793762 |doi=10.1210/edrv.19.5.0346 |url=}}</ref><ref name="urlHow Is Metabolic Syndrome Diagnosed? - NHLBI, NIH">{{cite web |url=https://www.nhlbi.nih.gov/health/health-topics/topics/ms/diagnosis |title=How Is Metabolic Syndrome Diagnosed? - NHLBI, NIH |format= |work= |accessdate=}}</ref> | |||
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{| style="border: 0px; font-size: 90%; margin: 3px;" align="center" | |||
! style="background:#4479BA; color: #FFFFFF;" | Conditions | |||
! style="background:#4479BA; color: #FFFFFF;" |Causes | |||
! style="background:#4479BA; color: #FFFFFF;" |Associated features | |||
! style="background:#4479BA; color: #FFFFFF;" |Diagnostic approach | |||
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| align="center" style="background:#DCDCDC;" |[[Metabolic syndrome X]] | |||
| style="padding: 5px 5px; background: #F5F5F5;" align="left" | | |||
*Familial/genetic | |||
*Obesity | |||
*Insulin resistance | |||
| style="padding: 5px 5px; background: #F5F5F5;" align="left" | | |||
* [[Obesity]] | |||
*[[Hypertension]] | |||
*[[PCOS]]/[[hyperandrogenism]] | |||
*[[Oligomenorrhea]]/[[hypogonadism]] | |||
*[[Dyslipidemia]] | |||
*[[Diabetes mellitus|Diabetes]]/[[Glucose intolerance]] | |||
| style="padding: 5px 5px; background: #F5F5F5;" align="left" | | |||
*Waist circumference | |||
*[[Lipoproteins|Low-density lipoproteins]] | |||
*[[Lipoproteins|High-density lipoproteins]] | |||
*[[Glucose tolerance test]] | |||
*[[Fasting blood sugar]] | |||
*[[HbA1c]] | |||
|- | |||
| align="center" style="background:#DCDCDC;" |[[Cushing's syndrome]] | |||
| style="padding: 5px 5px; background: #F5F5F5;" align="left" | | |||
*Iatrogenic | |||
*Pituitary adenoma | |||
*Adrenal tumor | |||
*Adrenal hyperplasia | |||
*Ectopic ACTH secretion | |||
| style="padding: 5px 5px; background: #F5F5F5;" align="left" | | |||
* [[Obesity]] | |||
*[[Hypertension]] | |||
*[[PCOS]]/[[hyperandrogenism]] | |||
*[[Oligomenorrhea]]/[[hypogonadism]] | |||
*[[Osteoporosis]] | |||
*[[Myopathy]]/cutaneous wasting | |||
*Neuropsychiatric problems | |||
*[[Kidney stone|Kidney stones]] | |||
| style="padding: 5px 5px; background: #F5F5F5;" align="left" | | |||
*24-hour urine cortisol | |||
*Midnight salivary cortisol | |||
*Low dose dexamethasone challenge test | |||
*CRH stimulation | |||
*High dose dexamethasone test | |||
*MRI brain | |||
*CT/MRI adrenals | |||
|- | |||
| align="center" style="background:#DCDCDC;" |[[Pseudo-Cushing's syndrome]] | |||
| style="padding: 5px 5px; background: #F5F5F5;" align="left" | | |||
*Obesity | |||
*Alcoholism | |||
*Depression | |||
*HIV | |||
| style="padding: 5px 5px; background: #F5F5F5;" align="left" | | |||
* [[Obesity]] | |||
*[[Hypertension]] | |||
*[[PCOS]]/[[hyperandrogenism]] | |||
*[[Oligomenorrhea]]/[[hypogonadism]] | |||
| style="padding: 5px 5px; background: #F5F5F5;" align="left" | | |||
*Urinary free cortisol | |||
*Midnight salivary cortisol | |||
*Low dose dexamethasone challenge test | |||
*[[Glucose tolerance test]] | |||
*Loperamide test | |||
|} | |||
==References== | ==References== | ||
Revision as of 20:23, 7 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Differentiating Metabolic Syndrome from other Diseases
The table below summarizes the findings that differentiate Cushing's disease from other conditions that may cause hypertension, hyperandrogenism, and obesity. Facial plethora, skin changes, osteoporosis, nephrolithiasis and neuropsychiatric conditions should raise the concern for Cushing's syndrome.[1][2][3][4]
References
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