Non-alcoholic fatty liver disease causes: Difference between revisions
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==Causes== | ==Causes== | ||
* Common causes in the development of NAFLD is related to [[obesity]] which will result in [[insulin resistance]] and [[metabolic syndrome]].<ref>{{Cite web|url=https://www.medscape.com/viewarticle/757336_2|title=Nonalcoholic Fatty Liver Disease|last=|first=|date=|website=|publisher=|access-date=}}</ref><ref name="pmid22338098">{{cite journal |vauthors=Sung KC, Jeong WS, Wild SH, Byrne CD |title=Combined influence of insulin resistance, overweight/obesity, and fatty liver as risk factors for type 2 diabetes |journal=Diabetes Care |volume=35 |issue=4 |pages=717–22 |year=2012 |pmid=22338098 |pmc=3308286 |doi=10.2337/dc11-1853 |url=}}</ref>It is estimated that approximately 80% of the obese people suffer from NAFLD.<ref>{{Cite web|url=https://www.mayoclinic.org/diseases-conditions/nonalcoholic-fatty-liver-disease/symptoms-causes/syc-20354567|title=Nonalcoholic fatty liver disease|last=|first=|date=|website=|publisher=|access-date=}}</ref> | |||
* Patients who are having [[type 2 diabetes mellitus]] are more prone to develop Nafld<ref>{{Cite web|url=https://www.medscape.com/viewarticle/757336_2|title=Nonalcoholic Fatty Liver Disease|last=|first=|date=|website=|publisher=|access-date=}}</ref><ref name="urlNonalcoholic Fatty Liver Disease & NASH | NIDDK">{{cite web |url=https://www.niddk.nih.gov/health-information/liver-disease/nafld-nash |title=Nonalcoholic Fatty Liver Disease & NASH | NIDDK |format= |work= |accessdate=}}</ref> | |||
*Less commonly Patients with [[hypertension]] and [[dyslipidemia]] are also associated with developing NAFLD | |||
===Secondary causes=== | ===Secondary causes=== | ||
[[NAFLD]] can also be caused by the following medications (termed secondary [[NAFLD]]): | [[NAFLD]] can also be caused by the following medications (termed secondary [[NAFLD]]): | ||
Revision as of 14:23, 21 November 2017
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Non-Alcoholic Fatty Liver Disease Microchapters |
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Differentiating Non-Alcoholic Fatty Liver Disease from other Diseases |
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Diagnosis |
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Treatment |
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Case studies |
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Non-alcoholic fatty liver disease causes On the Web |
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American Roentgen Ray Society Images of Non-alcoholic fatty liver disease causes |
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Directions to Hospitals Treating Non-alcoholic fatty liver disease |
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Risk calculators and risk factors for Non-alcoholic fatty liver disease causes |
Editor in Chief: Elliot Tapper, M.D., Beth Israel Deaconess Medical Center, C. Michael Gibson, M.S., M.D. [1]
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Overview
Oxidative stress, hormonal imbalances, endotoxemia and mitochondrial abnormalities may all be potential causes. It can be caused by some medications, and it is referred to as secondary NAFLD.
Causes
- Common causes in the development of NAFLD is related to obesity which will result in insulin resistance and metabolic syndrome.[1][2]It is estimated that approximately 80% of the obese people suffer from NAFLD.[3]
- Patients who are having type 2 diabetes mellitus are more prone to develop Nafld[4][5]
- Less commonly Patients with hypertension and dyslipidemia are also associated with developing NAFLD
Secondary causes
NAFLD can also be caused by the following medications (termed secondary NAFLD):
- Amiodarone
- Antiviral drugs (nucleoside analogues)
- Aspirin / NSAIDS
- Corticosteroids
- Methotrexate
- Nifedipine
- Perhexiline
- Tamoxifen
- Tetracycline
- Valproic acid
References
- ↑ "Nonalcoholic Fatty Liver Disease".
- ↑ Sung KC, Jeong WS, Wild SH, Byrne CD (2012). "Combined influence of insulin resistance, overweight/obesity, and fatty liver as risk factors for type 2 diabetes". Diabetes Care. 35 (4): 717–22. doi:10.2337/dc11-1853. PMC 3308286. PMID 22338098.
- ↑ "Nonalcoholic fatty liver disease".
- ↑ "Nonalcoholic Fatty Liver Disease".
- ↑ "Nonalcoholic Fatty Liver Disease & NASH | NIDDK".
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Non-Alcoholic Fatty Liver Disease Microchapters |
|
Differentiating Non-Alcoholic Fatty Liver Disease from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case studies |
|
Non-alcoholic fatty liver disease causes On the Web |
|
American Roentgen Ray Society Images of Non-alcoholic fatty liver disease causes |
|
Directions to Hospitals Treating Non-alcoholic fatty liver disease |
|
Risk calculators and risk factors for Non-alcoholic fatty liver disease causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief:
Please help WikiDoc by adding content here. It's easy! Click here to learn about editing.