Alcoholic liver disease laboratory findings: Difference between revisions
Jump to navigation
Jump to search
Irfan Dotani (talk | contribs) No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{Alcoholic liver disease}} | {{Alcoholic liver disease}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{MKA}} | ||
==Overview== | ==Overview== | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
=== | *Elevated liver enzymes:<ref name="pmid15535453">{{cite journal |vauthors=Marsano LS, Mendez C, Hill D, Barve S, McClain CJ |title=Diagnosis and treatment of alcoholic liver disease and its complications |journal=Alcohol Res Health |volume=27 |issue=3 |pages=247–56 |year=2003 |pmid=15535453 |doi= |url=}}</ref> | ||
**Aspartate aminotransferase (AST) level will be greater than that of Alanine aminotransferase (ALT). | |||
**AST and ALT levels both will be below 300 IU/ml. | |||
**The key to diagnosis of alcoholic liver disease is that the AST to ALT ratio will be greater than 2. | |||
*Elevated levels of gamma glutamyltransferase (GGT) will indicate heavy alcohol use and may also indicate liver injury. This test is sensitive but not specific.<ref name="pmid15535453">{{cite journal |vauthors=Marsano LS, Mendez C, Hill D, Barve S, McClain CJ |title=Diagnosis and treatment of alcoholic liver disease and its complications |journal=Alcohol Res Health |volume=27 |issue=3 |pages=247–56 |year=2003 |pmid=15535453 |doi= |url=}}</ref> | |||
*Elevated triglyceride levels (hypertriglyceridemia). | |||
*Elevated uric acid levels (hyperuricemia) | |||
*Low potassium levels (hypokalemia) | |||
*Low magnesium levels (hypomagnesemia) | |||
*Elevated index of red blood cell size; increased mean corpuscular erythrocyte volume (MCV) | |||
==2010 AASLD/ACG Alcoholic Liver Disease Guidelines (DO NOT EDIT)<ref name="urlwww.aasld.org">{{cite web |url=http://www.aasld.org/practiceguidelines/Documents/Bookmarked%20Practice%20Guidelines/AlcoholicLiverDisease1-2010.pdf |title=www.aasld.org |format= |work= |accessdate=2012-10-27}}</ref>== | ==2010 AASLD/ACG Alcoholic Liver Disease Guidelines (DO NOT EDIT)<ref name="urlwww.aasld.org">{{cite web |url=http://www.aasld.org/practiceguidelines/Documents/Bookmarked%20Practice%20Guidelines/AlcoholicLiverDisease1-2010.pdf |title=www.aasld.org |format= |work= |accessdate=2012-10-27}}</ref>== | ||
Revision as of 20:22, 18 December 2017
|
Alcoholic liver disease Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Alcoholic liver disease laboratory findings On the Web |
|
American Roentgen Ray Society Images of Alcoholic liver disease laboratory findings |
|
Risk calculators and risk factors for Alcoholic liver disease laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]
Overview
Laboratory Findings
- Elevated liver enzymes:[1]
- Aspartate aminotransferase (AST) level will be greater than that of Alanine aminotransferase (ALT).
- AST and ALT levels both will be below 300 IU/ml.
- The key to diagnosis of alcoholic liver disease is that the AST to ALT ratio will be greater than 2.
- Elevated levels of gamma glutamyltransferase (GGT) will indicate heavy alcohol use and may also indicate liver injury. This test is sensitive but not specific.[1]
- Elevated triglyceride levels (hypertriglyceridemia).
- Elevated uric acid levels (hyperuricemia)
- Low potassium levels (hypokalemia)
- Low magnesium levels (hypomagnesemia)
- Elevated index of red blood cell size; increased mean corpuscular erythrocyte volume (MCV)
2010 AASLD/ACG Alcoholic Liver Disease Guidelines (DO NOT EDIT)[2]
Laboratory Tests : Guidelines (DO NOT EDIT)[2]
| Class I |
| 1. " For patients with a history of alcohol abuse or excess and evidence of liver disease, further laboratory tests should be done to exclude other etiologies and to confirm the diagnosis. (Level of evidence: C) " |