Amyloidosis natural history, complications and prognosis

Amyloidosis Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification • Primary amyloidosis • Secondary amyloidosis • Familial amyloidosis • Wild-type (senile) amyloidosis • Cardiac amyloidosis • Beta-2 microglobulin related amyloidosis • Gelsolin related amyloidosis • Lysozyme amyloid related amyloidosis • Leucocyte cell-derived chemotaxin 2 related amyloidosis • Fibrinogen A alpha-chain associated amyloidosis
Pathophysiology
Causes
Differentiating Amyloidosis from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
Echocardiography and Ultrasound
CT scan
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Amyloidosis natural history, complications and prognosis On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Amyloidosis natural history, complications and prognosis All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Amyloidosis natural history, complications and prognosis
CDC on Amyloidosis natural history, complications and prognosis
Amyloidosis natural history, complications and prognosis in the news
Blogs on Amyloidosis natural history, complications and prognosis
Directions to Hospitals Treating Psoriasis
Risk calculators and risk factors for Amyloidosis natural history, complications and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Please help WikiDoc by adding content here. It's easy! Click here to learn about editing.

Overview

The complications of amyloidosis include hyposplenism, malabsorption syndrome, myopathy, proximal renal tubular acidosis and renal failure. The severity of the disease depends on the organs that are affected. When the heart and kidneys are involved, it may lead to organ failure and eventual death.

Complications

Possible complications of amyloidosis include:

• Hyposplenism
• Malabsorption syndrome
• Myopathy
• Proximal renal tubular acidosis
• Renal failure
• Vascular hemostatic disorder
• Chronic brain failure
• Nephrotic syndrome
• Myocarditis
• Restrictive cardiomyopathy
• Pulmonary fibrosis
• Autonomic neuropathy
• Pericardial effusion
• Congestive heart failure
• Endocrine failure (hormonal disorder)
• Respiratory failure
• Hypogonadic hypogonadism
• Death

Prognosis

The severity the disease depends on the organs that are affected. When the heart and kidney are involved, it may lead to organ failure and death. Body-wide (systemic) involvement can lead to death in 1 to 3 years.